Growth factors in breast cancer
RB Dickson, ME Lippman - Endocrine reviews, 1995 - academic.oup.com
I. Regulation of Mammary Cell Growth and Apoptosis A. Hormonal control of mammary
development, proliferation, and lactational defferentation D EVELOPMENT of the normal …
development, proliferation, and lactational defferentation D EVELOPMENT of the normal …
Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes
K Kok, SL Naylor, CHCM Buys - Advances in cancer research, 1997 - Elsevier
Publisher Summary This chapter discusses the methodological advantages and limitations
of the various approaches used to localize tumor suppressor genes on 3p, the short arm of …
of the various approaches used to localize tumor suppressor genes on 3p, the short arm of …
BRCA1 Mutations in Primary Breast and Ovarian Carcinomas
PA Futreal, Q Liu, D Shattuck-Eidens, C Cochran… - Science, 1994 - science.org
Loss of heterozygosity data from familial tumors suggest that BRCA1, a gene that confers
susceptibility to ovarian and early-onset breast cancer, encodes a tumor suppressor. The …
susceptibility to ovarian and early-onset breast cancer, encodes a tumor suppressor. The …
E‐cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.
Compelling experimental evidence exists for a potent invasion suppressor role of the cell‐
cell adhesion molecule E‐cadherin. In addition, a tumour suppressor effect has been …
cell adhesion molecule E‐cadherin. In addition, a tumour suppressor effect has been …
Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage
JN Marcus, P Watson, DL Page… - … Journal of the …, 1996 - Wiley Online Library
BACKGROUND The purpose of this investigation was to determine if there are pathobiologic
differences between BRCA1‐related and BRCA2‐related hereditary breast cancer (HBC) …
differences between BRCA1‐related and BRCA2‐related hereditary breast cancer (HBC) …
Hypermethylation of the CpG Island of Ras Association Domain Family 1A (RASSF1A), a Putative Tumor Suppressor Gene from the 3p21.3 Locus, Occurs in a Large …
R Dammann, G Yang, GP Pfeifer - Cancer research, 2001 - AACR
The human Ras association domain family 1A gene (RASSF1A), recently cloned from the
lung tumor suppressor locus 3p21. 3, was shown to be hypermethylated in primary lung …
lung tumor suppressor locus 3p21. 3, was shown to be hypermethylated in primary lung …
Loss of Expression and Aberrant Methylation of the CDH13 (H-Cadherin) Gene in Breast and Lung Carcinomas
KO Toyooka, S Toyooka, AK Virmani… - Cancer research, 2001 - AACR
Expression of some members of the cadherin family is reduced in several human tumors,
and CDH13 (H-cadherin), located on chromosome 16q24. 2–3, may function as a tumor …
and CDH13 (H-cadherin), located on chromosome 16q24. 2–3, may function as a tumor …
Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81
KR Schneider, RL Smith, EK O'Shea - Science, 1994 - science.org
A complex consisting of the cyclin-dependent kinase (CDK) PHO85 and the cyclin PHO80
phosphorylates and is thought to inactivate the transcription factor PHO4 when yeast cells …
phosphorylates and is thought to inactivate the transcription factor PHO4 when yeast cells …
H–cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer
SW Lee - Nature medicine, 1996 - nature.com
A newly identified gene, H–cadherin, is reported. H–cadherin encodes a protein related to
the cadherin superfamily of cell adhesion molecules, and its expression is shown to be …
the cadherin superfamily of cell adhesion molecules, and its expression is shown to be …
[图书][B] Fundamentals of Oncology, revised and expanded
HC Pitot - 2002 - taylorfrancis.com
Compiling significant advances from more than a decade of research, this text presents
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …