This review focuses on the contribution of white, brown, and perivascular adipose tissues to
the pathophysiology of obesity and its associated metabolic and vascular complications …

Objective. Several clinical studies have reported the application of dipeptidyl peptidase‐4
(DPP‐4) inhibitors as treatments for type 1 diabetes mellitus (T1DM). This study aims to …

Background: Increase in circulating dipeptidyl peptidase-4 (DPP4) activity and levels has
been reported to associate both with hyperglycemia and obesity. Here we aim to decipher …

Accumulating evidence shows that a gut-released hormone, the glucagon-like peptide-1
(GLP-1), has not only a glucose-lowering effect but also a renoprotective effect against …

Background A soluble form of CD26/dipeptidyl peptidase-IV (sCD26/DPP-IV) induces DPP-
IV enzymatic activity that degrades incretin. We investigated fasting serum levels of …

Cardiometabolic diseases are often associated with heightened levels of angiotensin II (Ang
II), which accounts for the observed oxidative stress, inflammation, and fibrosis …

Aims The inability of kidneys to prevent urinary protein leakage represents the earliest sign
of renal damage in diabetic kidney disease (DKD). Recent data suggest the possible …

Background/Aim: Amaranth is a source of several bioactive compounds, among which
peptides with inhibitory activity upon dipeptidyl peptidase IV (DPP-IV) have been reported …

Aims Recent studies have implicated possible contribution of adipocytokines in
development and progression of microvascular complications in patients with type 1 …

Type 1 diabetes (T1DM) is a disease characterized by autoimmune mediated destruction of
the insulin producing beta cells of endocrine pancreas. Beside insulin deficiency, T1DM is …