The C-terminal domain of RPB1 (CTD) orchestrates transcription by recruiting regulators to
RNA Pol II upon phosphorylation. With CTD driving condensate formation on gene loci, the …

Decades of scientific research have been devoted to unraveling the intricacies of eukaryotic
transcription since the groundbreaking discovery of eukaryotic RNA polymerases in the late …

The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a
regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 …

The repetitive heptads in the C-terminal domain (CTD) of RPB1, the largest subunit of RNA
Polymerase II (Pol II), play a critical role in the regulation of Pol II-based transcription. Recent …

RNA polymerase II (RNAP II) is one of the primary enzymes responsible for expressing
protein-encoding genes and some small nuclear RNAs. The enigmatic carboxy-terminal …

During eukaryotic transcription, RNA polymerase II undergoes dynamic post-translational
modifications on the C-terminal domain (CTD) of the largest subunit, generating an …

The critical role of site-specific phosphorylation in eukaryotic transcription has motivated
efforts to decipher the complex phosphorylation patterns exhibited by the carboxyl-terminal …

The repetitive C-terminal domain (CTD) of the largest subunit of RNA polymerase II (RNAPII)
becomes differentially phosphorylated throughout the transcription cycle. Here, we present a …

Identifying major histocompatibility complex (MHC) class I immunopeptide antigens
represents a key step in the development of immune-based targeted therapeutics and …

The whole part of the research in this thesis has already been published or the
corresponding manuscript is being under revision at the moment of working on this …