Direct oral anticoagulants (DOAC s), including the direct thrombin inhibitor, dabigatran, and
the direct factor Xa (FX a) inhibitors, rivaroxaban, apixaban and edoxaban, are approved for …

Oral vitamin K anticoagulation (warfarin, Coumadin, coumarin) has long been used for long-
term treatment and prophylaxis in a variety of clinical settings. Given the unpredictable …

Objectives During anticoagulant therapy, major bleeding is one of the most severe adverse
effects. This study aimed to evaluate the relationships between ABCB1, ABCG2, and …

In this report, combination of a mixed mode dispersive solid phase extraction with dispersive
liquid–liquid microextraction has been performed in order to the effective isolation of three …

Background: Direct oral anticoagulants (DOACs) are prescribed for systemic
anticoagulation. Fixed doses are recommended, but dose individualization may be …

ABCB1 SNP rs4148738 modulation of apixaban interindividual variability ABCB1 SNP
rs4148738 modulation of apixaban interindividual variability Thromb Res. 2016 Sep:145:24-6 …

Background Direct-acting oral anticoagulants (DOACs) are widely prescribed for stroke
prevention in patients with atrial fibrillation (AF). An important advantage of DOACs is that …

A novel electrochemical probe was established for the quantification of apixaban (APX) in
unprocessed plasma samples. Efficiently oxidized graphene oxide aerogels (EEGO-AGs) …

Remdesivir and apixaban have been included in the treatment guidelines of several
countries for severe COVID-19 infections. To date, no analytical method has been …

To establish a rapid and sensitive ultra performance liquid chromatography tandem mass
spectrometry (UPLC–MS/MS) method for the determination of rivaroxaban, apixaban and …