DNA binding studies of antifungal drug posaconazole using spectroscopic and molecular docking methods
The binding studies of DNA with small molecules have been an emerging field of research
all the time since DNA as the genetic material is a major biological target for various drugs …
all the time since DNA as the genetic material is a major biological target for various drugs …
The interaction mechanism of candidone with calf thymus DNA: A multi-spectroscopic and MD simulation study
In this investigation, the effects of candidone on the structure and conformation of DNA were
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
Investigation of the interaction between anticancer drug ibrutinib and double-stranded DNA by electrochemical and molecular docking techniques
Ibrutinib is Bruton's tyrosine kinase inhibitor that is generally used in the treatment of
lymphoma. The investigation of anticancer drug-double-stranded DNA (dsDNA) interaction …
lymphoma. The investigation of anticancer drug-double-stranded DNA (dsDNA) interaction …
Synthesis, characterization and biological applications of a new nano-sized binuclear copper (II) complex containing bathophenanthroline and ellagic acid as ligands
A new binuclear copper (II) complex, nano-[Cu 2-(DIP) 2-EA], was synthesized by using
bathophenanthroline and ellagic acid ligands in a multi-component/one-pot method, and …
bathophenanthroline and ellagic acid ligands in a multi-component/one-pot method, and …
Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer …
In the present study, a drug-like molecular hybrid structure between chalcone and
sulfonamide moieties was synthesized and characterized. The structural peculiarities of the …
sulfonamide moieties was synthesized and characterized. The structural peculiarities of the …
DNA groove binder and significant cytotoxic activity on human colon cancer cells: Potential of a dimeric zinc (II) phthalocyanine derivative
GS Batibay, GK Karaoglan, GG Kose… - Biophysical …, 2023 - Elsevier
The interaction of a multi-component system consisting of benzene-1, 4-diyldimethanimine-
bridged dimeric zinc-phthalocyanine groups (4OMPCZ) with calf thymus DNA (ct-DNA) was …
bridged dimeric zinc-phthalocyanine groups (4OMPCZ) with calf thymus DNA (ct-DNA) was …
Voltammetric studies on the interaction of ds-DNA with anti-cancer agents imatinib and erlotinib–Comparison of Au and Pt nanoparticle effects to drug-DNA complex …
DE Bayraktepe, C Yıldız, Z Yazan - Journal of Molecular Liquids, 2023 - Elsevier
The interactions of imatinib (IMA) and erlotinib (ERL) with calf-thymus double-stranded
deoxyribonucleic acid (ds-DNA) were studied by using monometallic (Au and Pt) and …
deoxyribonucleic acid (ds-DNA) were studied by using monometallic (Au and Pt) and …
Towards understanding of the interaction of certain carbapenems with protein via combined experimental and theoretical approach
The interactions of the recent carbapenems; ertapenem (ERP) and meropenem (MRP); with
serum albumin (SA) were closely investigated by a combined spectrofluorometric …
serum albumin (SA) were closely investigated by a combined spectrofluorometric …
Minor groove binding of antihistamine drug bilastine with calf thymus DNA: A molecular perspective with thermodynamics using experimental and theoretical methods
Molecular recognition which are driven by molecular interactions, is of great interest in drug
discovery and targeted drug delivery systems since drugs exhibit their medicinal …
discovery and targeted drug delivery systems since drugs exhibit their medicinal …
Mode of interaction of altretamine with calf thymus DNA: biophysical insights
Insights into drug-DNA interactions have importance in medicinal chemistry as it has a major
role in the evolution of new therapeutic drugs. Therefore, binding studies of small molecules …
role in the evolution of new therapeutic drugs. Therefore, binding studies of small molecules …