Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Lipids play a significant role in maintaining central nervous system (CNS) structure and
function, and the dysregulation of lipid metabolism is known to occur in many neurological …

Mass spectrometry-based quantitative lipidomics is an emerging field aiming to uncover the
intricate relationships between lipidomes and disease development. However, quantifying …

Perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are persistent
environmental contaminants that are of increasing public concern worldwide. However, their …

Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be
disappointing. Recent studies have shed light on how not just tumour cells, but also the …

Colorectal cancer (CRC) cells show some alterations in lipid metabolism, including an
increased fatty acid elongation. This study was focused on investigating the effect of a small …

The metabolic signature identification of colorectal cancer is critical for its early diagnosis
and therapeutic approaches that will significantly block cancer progression and improve …

Perfluorooctanesulfonic acid (PFOS) is a widely recognized environment pollutant known for
its high bioaccumulation potential and a long elimination half-life. Several studies have …

Cancerous cells synthesize most of their lipids de novo to keep up with their rapid growth
and proliferation. Fatty acid synthase (FAS) is a key enzyme in the lipogenesis pathway that …

Background Understanding the metabolic changes in colorectal cancer (CRC) and
exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and …