[HTML][HTML] RNA modifications: importance in immune cell biology and related diseases

L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Learning from the nexus of autoimmunity and cancer

D Mangani, D Yang, AC Anderson - Immunity, 2023 - cell.com
The immune system plays critical roles in both autoimmunity and cancer, diseases at
opposite ends of the immune spectrum. Autoimmunity arises from loss of T cell tolerance …

Targeting ferroptosis in gastric cancer: Strategies and opportunities

J Le, G Pan, C Zhang, Y Chen, AK Tiwari… - Immunological …, 2024 - Wiley Online Library
Ferroptosis is a novel form of programmed cell death morphologically, genetically, and
biochemically distinct from other cell death pathways and characterized by the accumulation …

[HTML][HTML] The implications of FASN in immune cell biology and related diseases

Y Xiao, Y Yang, H Xiong, G Dong - Cell Death & Disease, 2024 - nature.com
Fatty acid metabolism, particularly fatty acid synthesis, is a very important cellular
physiological process in which nutrients are used for energy storage and biofilm synthesis …

[HTML][HTML] The role of iron metabolism in the pathogenesis and treatment of multiple sclerosis

E Duarte-Silva, SG Meuth, CA Peixoto - Frontiers in immunology, 2023 - frontiersin.org
Multiple sclerosis is a severe demyelinating disease mediated by cells of the innate and
adaptive immune system, especially pathogenic T lymphocytes that produce the pro …

Metabolic regulation and function of T helper cells in neuroinflammation

M Spiljar, VK Kuchroo - Seminars in Immunopathology, 2022 - Springer
Neuroinflammatory conditions such as multiple sclerosis (MS) are initiated by pathogenic
immune cells invading the central nervous system (CNS). Autoreactive CD4+ T helper cells …

[HTML][HTML] Antibiotic-induced gut dysbiosis and autoimmune disease: A systematic review of preclinical studies

MM Gobbo, MB Bomfim, WY Alves, KC Oliveira… - Autoimmunity …, 2022 - Elsevier
Antibiotic-induced gut dysbiosis is believed to be associated with the onset and
development of autoimmune diseases. To evaluate microbiota's variations triggered by …

Autoreactive IgE: pathogenic role and therapeutic target in autoimmune diseases

N Charles, I Kortekaas‐Krohn, E Kocaturk, J Scheffel… - Allergy, 2023 - Wiley Online Library
Autoimmunity is the break of tolerance to self‐antigens that leads to organ‐specific or
systemic diseases often characterized by the presence of pathogenic autoreactive …

[HTML][HTML] Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells

DS Shin, S Ratnapriya, CN Cashin, LF Kuhn… - Cell reports, 2023 - cell.com
Self-antigen-specific T cells are prevalent in the mature adaptive immune system but are
regulated through multiple mechanisms of tolerance. However, inflammatory conditions …

[HTML][HTML] Bioinformatics analyses of combined databases identify shared differentially expressed genes in cancer and autoimmune disease

Y Sui, S Li, XQ Fu, ZJ Zhao, S Xing - Journal of Translational Medicine, 2023 - Springer
Background Inadequate immunity caused by poor immune surveillance leads to
tumorigenesis, while excessive immunity due to breakdown of immune tolerance causes …