Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials

D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

K Prame Kumar, AJ Nicholls, CHY Wong - Cell and tissue research, 2018 - Springer
Neutrophils are becoming recognized as highly versatile and sophisticated cells that display
de novo synthetic capacity and potentially prolonged lifespan. Emerging concepts such as …

The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens

A Ulfig, LI Leichert - Cellular and Molecular Life Sciences, 2021 - Springer
Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …

Roles of PAD4 and NETosis in experimental atherosclerosis and arterial injury: implications for superficial erosion

G Franck, TL Mawson, EJ Folco, R Molinaro… - Circulation …, 2018 - Am Heart Assoc
Rationale: Neutrophils likely contribute to the thrombotic complications of human
atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local …

Immune responses to implants–a review of the implications for the design of immunomodulatory biomaterials

S Franz, S Rammelt, D Scharnweber, JC Simon - Biomaterials, 2011 - Elsevier
A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

The multifaceted roles neutrophils play in the tumor microenvironment

RV Sionov, ZG Fridlender, Z Granot - Cancer microenvironment, 2015 - Springer
Neutrophils are myeloid cells that constitute 50–70% of all white blood cells in the human
circulation. Traditionally, neutrophils are viewed as the first line of defense against infections …

Multiple roles for neutrophils in atherosclerosis

O Soehnlein - Circulation research, 2012 - Am Heart Assoc
Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

Domesticating the foreign body response: Recent advances and applications

O Veiseh, AJ Vegas - Advanced drug delivery reviews, 2019 - Elsevier
The foreign body response is an immunological process that leads to the rejection of
implanted devices and presents a fundamental challenge to their performance, durability …

Neutrophils: Cinderella of innate immune system

V Kumar, A Sharma - International immunopharmacology, 2010 - Elsevier
Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …