Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …

Protein modifications provide cells with exquisite temporal and spatial control of protein
function. Ubiquitin is among the most important modifiers, serving both to target hundreds of …

Peroxisomes account for~ 35% of total H2O2 generation in mammalian tissues. Peroxisomal
ACOX 1 (acyl‐CoA oxidase 1) is the first and rate‐limiting enzyme in fatty acid β‐oxidation …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

The developmental rapidity of nanotechnology poses higher risks of exposure to humans
and the environment through manufactured nanomaterials. The multitude of biological …

Peroxisomes are eukaryotic organelles important for the metabolism of long-chain fatty
acids,. Here we show that in numerous fungal species, several core enzymes of glycolysis …

Peroxisomal biogenesis disorders (PBDs) are genetic disorders of peroxisome biogenesis
and metabolism that are characterized by profound developmental and neurological …

Peroxisomes represent so-called “multipurpose organelles” as they contribute to various
anabolic as well as catabolic pathways. Thus, with respect to the physiological …

In Alzheimer's disease (AD) and dementia of the Alzheimer's type (DAT), the role played by
peroxisomes is not well known. Peroxisomes are present in all eukaryotic cells, with the …

Despite their distinct biological functions, there is a surprising similarity between the
composition of the machinery that imports proteins into peroxisomes and the machinery that …