Single-and multifraction stereotactic radiosurgery dose/volume tolerances of the brain

MT Milano, J Grimm, A Niemierko, SG Soltys… - International Journal of …, 2021 - Elsevier
Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy investigating normal tissue complication probability (NTCP) …

Treatment for brain metastases: ASCO-SNO-ASTRO guideline

MA Vogelbaum, PD Brown, H Messersmith… - 2022 - academic.oup.com
Purpose To provide guidance to clinicians regarding therapy for patients with brain
metastases from solid tumors. Methods ASCO convened an Expert Panel and conducted a …

Radiation-induced immunity and toxicities: the versatility of the cGAS-STING pathway

J Constanzo, J Faget, C Ursino, C Badie… - Frontiers in …, 2021 - frontiersin.org
In the past decade, radiation therapy (RT) entered the era of personalized medicine,
following the striking improvements in radiation delivery and treatment planning …

Single versus multifraction stereotactic radiosurgery for large brain metastases: an international meta-analysis of 24 trials

EJ Lehrer, JL Peterson, NG Zaorsky, PD Brown… - International Journal of …, 2019 - Elsevier
Purpose Multifraction (MF) stereotactic radiosurgery (SRS) purportedly reduces
radionecrosis risk over single-fraction (SF) SRS in the treatment of large brain metastases …

Radiomics as prognostic factor in brain metastases treated with Gamma Knife radiosurgery

CY Huang, CC Lee, HC Yang, CJ Lin, HM Wu… - Journal of Neuro …, 2020 - Springer
Abstract Purpose Gamma Knife radiosurgery (GKRS) is a non-invasive procedure for the
treatment of brain metastases. This study sought to determine whether radiomic features of …

Multidisciplinary patient-centered management of brain metastases and future directions

JD Palmer, DM Trifiletti, V Gondi, M Chan… - Neuro-Oncology …, 2020 - academic.oup.com
The incidence of brain metastasis is increasing as improvements in systemic therapy lead to
increased survival. This provides new and challenging clinical decisions for patients who …

Efficacy and safety of stereotactic radiosurgery for brainstem metastases: a systematic review and meta-analysis

WC Chen, UH Baal, JD Baal, JS Pai, L Boreta… - JAMA …, 2021 - jamanetwork.com
Importance Owing to the proximity to critical neurologic structures, treatment options for
brainstem metastases (BSM) are limited, and BSM growth can cause acute morbidity or …

Proton and heavy particle intracranial radiosurgery

EJ Lehrer, AV Prabhu, KK Sindhu, S Lazarev… - Biomedicines, 2021 - mdpi.com
Stereotactic radiosurgery (SRS) involves the delivery of a highly conformal ablative dose of
radiation to both benign and malignant targets. This has traditionally been accomplished in …

Neurosurgical management of brain metastases

SD Ferguson, KM Wagner, SS Prabhu… - Clinical & Experimental …, 2017 - Springer
Brain metastases present a significant public health issue, affecting more than 100,000
patients per year in the US and result in significant morbidity. Brain metastases can occur in …

Preoperative stereotactic radiosurgery for glioblastoma

EJ Lehrer, H Ruiz-Garcia, AD Nehlsen, KK Sindhu… - Biology, 2022 - mdpi.com
Simple Summary Stereotactic radiosurgery (SRS) is a multidisciplinary neurosurgical and
radiation technique that allows for the delivery of a highly conformal dose of ionizing …