While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

The intrauterine and early postnatal periods represent key developmental stages in which
an organism is highly susceptible to being permanently influenced by maternal factors and …

Due to their multidirectional influence, adipocytokines are currently the subject of numerous
intensive studies. Significant impact applies to many processes, both physiological and …

Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …

Obesity is now recognized as a worldwide epidemic. An inadequate diet and reduced
physical activity are acknowledged as the leading causes of excess body weight. Despite …

Lifestyle changes have made metabolic disorders as one of the major threats to life. Growing
evidence demonstrates that obesity and diabetes disrupt the reproductive system by …

Inflammation and oxidative stress are essential components in a myriad of pathogenic
entities that lead to metabolic and chronic diseases. Moreover, inflammation in its different …

Apelin (APLN) is an endogenous ligand of the G protein-coupled receptor APJ (APLNR).
APLN has been implicated in the development of multiple tumours. Herein, we determined …

Obesity reaches up to epidemic proportions globally and increases the risk for a wide
spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension …