The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …

Increasing oxidative stress, a major characteristic of aging, has been implicated in a variety
of age-related pathologies. In aging, oxidant production from several sources is increased …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

Myocardial ischemia or reperfusion increases the generation of reactive oxygen species
(ROS) from damaged mitochondria, NADPH oxidases, xanthine oxidase, and inflammation …

This review is aimed at summarizing the new findings about the multiple benefits of exercise
on cardiovascular disease (CVD). We pay attention to the prevalence and risk factors of …

Brain cells normally respond adaptively to oxidative stress or bioenergetic challenges,
resulting from ongoing activity in neuronal circuits. During aging and in neurodegenerative …

Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …