How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond

J Rimando, SR McCurdy, L Luznik - Blood, 2023 - ashpublications.org
Advances in conditioning, graft-versus-host disease (GVHD) prophylaxis and antimicrobial
prophylaxis have improved the safety of allogeneic hematopoietic cell transplantation (HCT) …

Does PTCY increase the risk of infections?

M Mikulska, C Bartalucci, AM Raiola, C Oltolini - Blood Reviews, 2023 - Elsevier
PTCY has been mainly used in haploidentical transplant (haploHSCT), but its use in
matched donors allowed better evaluation of infectious risk conferred separately by PTCY or …

[HTML][HTML] American Society for Transplantation and Cellular Therapy series:# 3—prevention of cytomegalovirus infection and disease after hematopoietic cell …

M Hakki, SL Aitken, L Danziger-Isakov… - … and Cellular Therapy, 2021 - Elsevier
Abstract The Practice Guidelines Committee of the American Society for Transplantation and
Cellular Therapy partnered with its Transplant Infectious Disease Special Interest Group to …

[HTML][HTML] Letermovir discontinuation at day 100 after allogeneic stem cell transplant is associated with increased CMV-related mortality

LW Liu, A Yn, F Gao, M Olson, M Crain… - … and Cellular Therapy, 2022 - Elsevier
Letermovir is approved by the Food and Drug Administration for cytomegalovirus (CMV)
prophylaxis in CMV seropositive recipients of allogeneic stem cell transplantation (alloSCT) …

Cytomegalovirus breakthrough and resistance during letermovir prophylaxis

GA Perchetti, MA Biernacki, H Xie, J Castor… - Bone Marrow …, 2023 - nature.com
Letermovir is a relatively new antiviral for prophylaxis against cytomegalovirus (CMV) after
allogeneic hematopoietic cell transplantation (HCT). CMV-seropositive HCT recipients who …

Post-transplant cyclophosphamide in one-antigen mismatched unrelated donor transplantation versus haploidentical transplantation in acute myeloid leukemia: a …

G Battipaglia, JE Galimard, M Labopin… - Bone marrow …, 2022 - nature.com
Abstract Whether to choose Haploidentical (Haplo) or one-antigen mismatched unrelated
donor (1Ag-MMUD) hematopoietic cell transplantation (HCT) with post-transplant …

The promising efficacy of a risk-based letermovir use strategy in CMV-positive allogeneic hematopoietic cell recipients

M Sourisseau, E Faure, H Béhal, P Chauvet… - Blood …, 2023 - ashpublications.org
Letermovir is the first approved drug for cytomegalovirus (CMV) infection prophylaxis in adult
patients who are CMV positive undergoing allogeneic hematopoietic cell transplantation …

[HTML][HTML] Increased infections and delayed CD4+ T cell but faster B cell immune reconstitution after post-transplantation cyclophosphamide compared to conventional …

F Khimani, P Ranspach, H Elmariah, J Kim… - … and Cellular Therapy, 2021 - Elsevier
Post-transplantation cyclophosphamide (PTCy) is being increasingly used for graft-versus-
host disease (GVHD) prophylaxis after allogeneic hematopoietic cell transplantation (allo …

How I prevent viral reactivation in high-risk patients

SS Dadwal, GA Papanicolaou… - Blood, The Journal of …, 2023 - ashpublications.org
Preventing viral infections at an early stage is a key strategy for successfully improving
transplant outcomes. Preemptive therapy and prophylaxis with antiviral agents have been …

Human herpesvirus 6–specific T-cell immunity in allogeneic hematopoietic stem cell transplant recipients

M Noviello, F Lorentino, E Xue, S Racca… - Blood …, 2023 - ashpublications.org
Abstract Human herpesvirus 6 (HHV-6) can reactivate after allogeneic hematopoietic stem
cell transplant (allo-HSCT) and may lead to severe symptoms. HHV-6–specific immune …