[HTML][HTML] Effects of anti-diabetic drugs on fracture risk: a systematic review and network meta-analysis

YS Zhang, YD Zheng, Y Yuan, SC Chen… - Frontiers in …, 2021 - frontiersin.org
Purpose Available data on the effects of anti-diabetic drugs on fracture risk are contradictory.
Therefore, our study aimed to analyze all available data on the effects of anti-diabetic drugs …

An update on therapies for the treatment of diabetes-induced osteoporosis

S Mohsin, MMYH Baniyas… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Currently, 424 million people aged between 20 and 79 years worldwide are
diabetic. More than 25% of adults aged over 65 years in North America have Type 2 …

Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: activating integrin/TGF-β co-signaling of MSCs while …

RK Singh, DS Yoon, N Mandakhbayar, C Li, AG Kurian… - Biomaterials, 2022 - Elsevier
Regenerating defective bone in patients with diabetes mellitus remains a significant
challenge due to high blood glucose level and oxidative stress. Here we aim to tackle this …

The safety of gliptins: updated data in 2018

AJ Scheen - Expert opinion on drug safety, 2018 - Taylor & Francis
ABSTRACT Introduction: Dipeptidyl peptidase-4 inhibitors (DPP-4is) are generally
considered as glucose-lowering agents with a safe profile in type 2 diabetes. Areas covered …

[HTML][HTML] Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control

ME Youssef, G Yahya, MS Popoviciu, S Cavalu… - International Journal of …, 2023 - mdpi.com
The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …

[HTML][HTML] Hesperidin, a plant flavonoid accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats: Role of TGF-ß/Smads and Ang-1/Tie-2 …

W Li, AD Kandhare, AA Mukherjee, SL Bodhankar - EXCLI journal, 2018 - ncbi.nlm.nih.gov
Background: Delayed wound healing is a diverse, multifactorial, complex and inter-related
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …

Diabetes pharmacotherapy and effects on the musculoskeletal system

E Kalaitzoglou, JL Fowlkes, I Popescu… - … research and reviews, 2019 - Wiley Online Library
Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Relationship between metabolic syndrome and bone health–an evaluation of epidemiological studies and mechanisms involved

KY Chin, SK Wong, SO Ekeuku… - … , Metabolic Syndrome and …, 2020 - Taylor & Francis
Metabolic syndrome (MetS) and osteoporosis are two medical problems plaguing the
ageing populations worldwide. Though seemingly distinctive to each other, metabolic …

Synthesis, molecular docking and QSAR study of thiazole clubbed pyrazole hybrid as α-amylase inhibitor

M Duhan, R Singh, M Devi, J Sindhu… - Journal of …, 2021 - Taylor & Francis
In search of potent α-amylase inhibitors, herein we report the synthesis, molecular docking
and QSAR study of some thiazole clubbed pyrazole hybrids (TCPH) ie, 1-((1-phenyl-3-aryl-1 …

Angiogenic and osteogenic effects of flavonoids in bone regeneration

A Shanmugavadivu… - Biotechnology and …, 2022 - Wiley Online Library
Bone is a highly vascularized tissue that relies on a close spatial and temporal interaction
between blood vessels and bone cells. As a result, angiogenesis is critical for bone …