[HTML][HTML] Dietary sources and bioactivities of melatonin

X Meng, Y Li, S Li, Y Zhou, RY Gan, DP Xu, HB Li - Nutrients, 2017 - mdpi.com
Insomnia is a serious worldwide health threat, affecting nearly one third of the general
population. Melatonin has been reported to improve sleep efficiency and it was found that …

[HTML][HTML] Kidney damage caused by obesity and its feasible treatment drugs

M Wang, Z Wang, Y Chen, Y Dong - International journal of molecular …, 2022 - mdpi.com
The rapid growth of obesity worldwide has made it a major health problem, while the
dramatic increase in the prevalence of obesity has had a significant impact on the …

Obesity and chronic kidney disease

Z Jiang, Y Wang, X Zhao, H Cui… - American Journal …, 2023 - journals.physiology.org
The prevalence of obesity has increased dramatically during the past decades, which has
been a major health problem. Since 1975, the number of people with obesity worldwide has …

Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats

VU Nna, ABA Bakar, MRMLM Lazin… - Food and chemical …, 2018 - Elsevier
Diabetes mellitus is characterized by hyperglycemia which causes oxidative stress. Propolis
has been reported to have antihyperglycemic and antioxidant potentials. The present study …

[HTML][HTML] Targeting mitochondria and reactive oxygen species-driven pathogenesis in diabetic nephropathy

R Lindblom, G Higgins, M Coughlan… - The review of diabetic …, 2015 - ncbi.nlm.nih.gov
Diabetic kidney disease is one of the major microvascular complications of both type 1 and
type 2 diabetes mellitus. Approximately 30% of patients with diabetes experience renal …

Anti-inflammatory effects of melatonin in obesity and hypertension

NJ Prado, L Ferder, W Manucha, ER Diez - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …

[HTML][HTML] Chronic running exercise alleviates early progression of nephropathy with upregulation of nitric oxide synthases and suppression of glycation in Zucker …

D Ito, P Cao, T Kakihana, E Sato, C Suda, Y Muroya… - PloS one, 2015 - journals.plos.org
Exercise training is known to exert multiple beneficial effects including renal protection in
type 2 diabetes mellitus and obesity. However, the mechanisms regulating these actions …

Down‐regulation of steroidogenesis‐related genes and its accompanying fertility decline in streptozotocin‐induced diabetic male rats: ameliorative effect of metformin

VU Nna, ABA Bakar, A Ahmad, M Mohamed - Andrology, 2019 - Wiley Online Library
Background Metformin has long been used for glycemic control in diabetic state. Recently,
other benefits of metformin beyond blood glucose regulation have emerged. Objectives To …

Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats

VU Nna, ABA Bakar, M Mohamed - Life sciences, 2018 - Elsevier
Aims Hepatic oxidative stress and weak antioxidant defence system resulting in hepatic
lesion, has been reported in diabetic rats. The present study investigated the possible …

[HTML][HTML] Protective and therapeutic effects of orlistat on metabolic syndrome and oxidative stress in high-fat diet-induced metabolic dysfunction-associated fatty liver …

Z Zakaria, ZA Othman, J Bagi Suleiman, NAC Jalil… - Veterinary …, 2021 - mdpi.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is an excessive buildup of liver
lipids closely associated with various kinds of undesirable metabolic effects and oxidative …