Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2019 - pubs.rsc.org
Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …

Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands

WDJ Tremlett, DM Goodman, TR Steel, S Kumar… - Coordination Chemistry …, 2021 - Elsevier
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Reactions of secondary propargylamines with heteroallenes for the synthesis of diverse heterocycles

VA Peshkov, OP Pereshivko, AA Nechaev… - Chemical Society …, 2018 - pubs.rsc.org
This focused review aims to summarize recent developments in the processes involving
additions of secondary propargylamines to various heteroallenes and subsequent transition …

[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

Catalytic synthesis of cyclic guanidines via hydrogen atom transfer and radical-polar crossover

S Ohuchi, H Koyama, H Shigehisa - ACS Catalysis, 2021 - ACS Publications
Cyclic guanidines are found in many biologically active compounds and natural products.
Further, the formation of the atypical seven-membered ring of cyclic guanidine remains …

Solving the conundrum: Widespread proteins annotated for urea metabolism in bacteria are carboxyguanidine deiminases mediating nitrogen assimilation from …

NO Schneider, LJ Tassoulas, D Zeng, AJ Laseke… - Biochemistry, 2020 - ACS Publications
Free guanidine is increasingly recognized as a relevant molecule in biological systems.
Recently, it was reported that urea carboxylase acts preferentially on guanidine, and …

Heterologous expression of cryptomaldamide in a cyanobacterial host

A Taton, A Ecker, B Diaz, NA Moss… - ACS Synthetic …, 2020 - ACS Publications
Filamentous marine cyanobacteria make a variety of bioactive molecules that are produced
by polyketide synthases, nonribosomal peptide synthetases, and hybrid pathways that are …

Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics

Y Zong, F Fang, KJ Meyer, L Wang, Z Ni, H Gao… - Nature …, 2019 - nature.com
Teixobactin represents a new class of antibiotics with novel structure and excellent activity
against Gram-positive pathogens and Mycobacterium tuberculosis. Herein, we report a one …

Transformation of carbodiimides to guanidine derivatives facilitated by gallylenes

VA Dodonov, L Xiao, OA Kushnerova… - Chemical …, 2020 - pubs.rsc.org
The reductive coupling of carbodiimides RNCNR (R= 2, 6-iPr2C6H3, Cy, iPr) by using [(dpp-
bian) GaNa (dme) 2](1);[(dpp-dad) GaNa (thf) 3](2a) and [(dpp-dad) GaK (thf) 4Ga (dpp …