A roadmap to increase diversity in genomic studies
Two decades ago, the sequence of the first human genome was published. Since then,
advances in genome technologies have resulted in whole-genome sequencing and …
advances in genome technologies have resulted in whole-genome sequencing and …
[HTML][HTML] Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare
Precision Medicine implies a deep understanding of inter-individual differences in health
and disease that are due to genetic and environmental factors. To acquire such …
and disease that are due to genetic and environmental factors. To acquire such …
Rights, interests and expectations: Indigenous perspectives on unrestricted access to genomic data
Addressing Indigenous rights and interests in genetic resources has become increasingly
challenging in an open science environment that promotes unrestricted access to genomic …
challenging in an open science environment that promotes unrestricted access to genomic …
Prioritizing diversity in human genomics research
LA Hindorff, VL Bonham, LC Brody… - Nature Reviews …, 2018 - nature.com
Recent studies have highlighted the imperatives of including diverse and under-represented
individuals in human genomics research and the striking gaps in attaining that inclusion …
individuals in human genomics research and the striking gaps in attaining that inclusion …
Lack of diversity in genomic databases is a barrier to translating precision medicine research into practice
LG Landry, N Ali, DR Williams, HL Rehm… - Health Affairs, 2018 - healthaffairs.org
Precision medicine is predicted to revolutionize the clinical practice of medicine, in part by
using molecular biomarkers to assess patients' risk, prognosis, and therapeutic response …
using molecular biomarkers to assess patients' risk, prognosis, and therapeutic response …
Stress-related biosocial mechanisms of discrimination and African American health inequities
BJ Goosby, JE Cheadle… - Annual Review of …, 2018 - annualreviews.org
This review describes stress-related biological mechanisms linking interpersonal racism to
life course health trajectories among African Americans. Interpersonal racism, a form of …
life course health trajectories among African Americans. Interpersonal racism, a form of …
Opportunistic genomic screening. Recommendations of the European society of human genetics
G de Wert, W Dondorp, A Clarke… - European Journal of …, 2021 - nature.com
If genome sequencing is performed in health care, in theory the opportunity arises to take a
further look at the data: opportunistic genomic screening (OGS). The European Society of …
further look at the data: opportunistic genomic screening (OGS). The European Society of …
Genetics of obsessive-compulsive disorder
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …
The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology
Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading
causes of cancer death. The incidence, pathological features, and clinical outcomes in …
causes of cancer death. The incidence, pathological features, and clinical outcomes in …
The clinical sequencing evidence-generating research consortium: integrating genomic sequencing in diverse and medically underserved populations
LM Amendola, JS Berg, CR Horowitz, F Angelo… - The American Journal of …, 2018 - cell.com
The Clinical Sequencing Evidence-Generating Research (CSER) consortium, now in its
second funding cycle, is investigating the effectiveness of integrating genomic (exome or …
second funding cycle, is investigating the effectiveness of integrating genomic (exome or …