A roadmap to increase diversity in genomic studies

S Fatumo, T Chikowore, A Choudhury, M Ayub… - Nature medicine, 2022 - nature.com
Two decades ago, the sequence of the first human genome was published. Since then,
advances in genome technologies have resulted in whole-genome sequencing and …

[HTML][HTML] Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare

D Cirillo, S Catuara-Solarz, C Morey, E Guney… - NPJ digital …, 2020 - nature.com
Precision Medicine implies a deep understanding of inter-individual differences in health
and disease that are due to genetic and environmental factors. To acquire such …

Rights, interests and expectations: Indigenous perspectives on unrestricted access to genomic data

M Hudson, NA Garrison, R Sterling, NR Caron… - Nature Reviews …, 2020 - nature.com
Addressing Indigenous rights and interests in genetic resources has become increasingly
challenging in an open science environment that promotes unrestricted access to genomic …

Prioritizing diversity in human genomics research

LA Hindorff, VL Bonham, LC Brody… - Nature Reviews …, 2018 - nature.com
Recent studies have highlighted the imperatives of including diverse and under-represented
individuals in human genomics research and the striking gaps in attaining that inclusion …

Lack of diversity in genomic databases is a barrier to translating precision medicine research into practice

LG Landry, N Ali, DR Williams, HL Rehm… - Health Affairs, 2018 - healthaffairs.org
Precision medicine is predicted to revolutionize the clinical practice of medicine, in part by
using molecular biomarkers to assess patients' risk, prognosis, and therapeutic response …

Stress-related biosocial mechanisms of discrimination and African American health inequities

BJ Goosby, JE Cheadle… - Annual Review of …, 2018 - annualreviews.org
This review describes stress-related biological mechanisms linking interpersonal racism to
life course health trajectories among African Americans. Interpersonal racism, a form of …

Opportunistic genomic screening. Recommendations of the European society of human genetics

G de Wert, W Dondorp, A Clarke… - European Journal of …, 2021 - nature.com
If genome sequencing is performed in health care, in theory the opportunity arises to take a
further look at the data: opportunistic genomic screening (OGS). The European Society of …

Genetics of obsessive-compulsive disorder

B Mahjani, K Bey, J Boberg, C Burton - Psychological Medicine, 2021 - cambridge.org
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …

The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology

KA Hirko, G Rocque, E Reasor, A Taye, A Daly… - BMC medicine, 2022 - Springer
Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading
causes of cancer death. The incidence, pathological features, and clinical outcomes in …

The clinical sequencing evidence-generating research consortium: integrating genomic sequencing in diverse and medically underserved populations

LM Amendola, JS Berg, CR Horowitz, F Angelo… - The American Journal of …, 2018 - cell.com
The Clinical Sequencing Evidence-Generating Research (CSER) consortium, now in its
second funding cycle, is investigating the effectiveness of integrating genomic (exome or …