Cryptococcus interactions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

SA Johnston, RC May - Cellular microbiology, 2013 - Wiley Online Library
C ryptococcus is a potentially fatal fungal pathogen and a leading cause of death in
immunocompromised patients. As an opportunistic and facultative intracellular pathogen of …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

Molecular mechanisms of cryptococcal meningitis

TB Liu, DS Perlin, C Xue - Virulence, 2012 - Taylor & Francis
Fungal meningitis is a serious disease caused by a fungal infection of the central nervous
system (CNS) mostly in individuals with immune system deficiencies. Fungal meningitis is …

Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides

CH Li, M Cervantes, DJ Springer, T Boekhout… - PLoS …, 2011 - journals.plos.org
Mucor circinelloides is a zygomycete fungus and an emerging opportunistic pathogen in
immunocompromised patients, especially transplant recipients and in some cases otherwise …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Addressing microbial resistance worldwide: challenges over controlling life-threatening fungal infections

L Martins-Santana, CP Rezende, A Rossi… - Pathogens, 2023 - mdpi.com
Fungal infections are a serious global concern because of their ability to spread and
colonize host tissues in immunocompromised individuals. Such infections have been …

Ploidy variation in fungi: polyploidy, aneuploidy, and genome evolution

RT Todd, A Forche, A Selmecki - Microbiology spectrum, 2017 - Am Soc Microbiol
The ability of an organism to replicate and segregate its genome with high fidelity is vital to
its survival and for the production of future generations. Errors in either of these steps …

The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model

P Ngamskulrungroj, Y Chang, E Sionov… - MBio, 2012 - Am Soc Microbiol
Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the
primary pathogen Cryptococcus gattii. Epidemiological studies suggest that patients infected …

Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals

N Trevijano-Contador, HC de Oliveira… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of
the cells during infection. In particular, this process can occur by enlarging the size of the …

Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody

AB Dalia, JN Weiser - Cell host & microbe, 2011 - cell.com
The complement system, which functions by lysing pathogens directly or by promoting their
uptake by phagocytes, is critical for controlling many microbial infections. Here, we show that …