[HTML][HTML] Palindromes in DNA—a risk for genome stability and implications in cancer

M Svetec Miklenić, IK Svetec - International journal of molecular sciences, 2021 - mdpi.com
A palindrome in DNA consists of two closely spaced or adjacent inverted repeats. Certain
palindromes have important biological functions as parts of various cis-acting elements and …

Quantitative assessment reveals the dominance of duplicated sequences in germline-derived extrachromosomal circular DNA

L Mouakkad-Montoya, MM Murata… - Proceedings of the …, 2021 - National Acad Sciences
Extrachromosomal circular DNA (eccDNA) originates from linear chromosomal DNA in
various human tissues under physiological and disease conditions. The genomic origins of …

Anti-inflammatory and anti-apoptotic effects of Shaoyao decoction on X-ray radiation-induced enteritis of C57BL/6 mice

Z Li, Y Gao, L Du, Y Yuan, W Huang, X Fu… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance As a typical heat-clearing prescription, Shaoyao decoction
(SYD) has a robust function of clearing viscera heat for the treatment of several intestinal …

[HTML][HTML] Bioinformatic identification of genomic instability-associated lncRNAs signatures for improving the clinical outcome of cervical cancer by a prognostic model

J Zhang, N Ding, Y He, C Tao, Z Liang, W Xin… - Scientific Reports, 2021 - nature.com
The research is executed to analyze the connection between genomic instability-associated
long non-coding RNAs (lncRNAs) and the prognosis of cervical cancer patients. We set a …

[HTML][HTML] Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

SR Dehkordi, ITL Wong, J Ni, J Luebeck, K Zhu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Oncogene amplification is a major driver of cancer pathogenesis. Breakage fusion bridge
(BFB) cycles, like extrachromosomal DNA (ecDNA), can lead to high copy numbers of …

Statistical mining of triple-negative breast cancer-specific nanobodies among huge libraries from immunized alpacas

R Maeda, H Yamazaki, R Kobayashi, S Yamamoto… - bioRxiv, 2023 - biorxiv.org
Breast cancer can be classified into several types according to the expression patterns of
human epidermal growth factor receptor 2 (Her2), oestrogen receptor (ER), and …

Publications from Juntendo University Graduate School of Medicine, 2021 [4/6]

UHRI Severe - Ann Surg, 2021 - jstage.jst.go.jp
Juntendo Medical Journal 69 (6), 2023 atic surgical fellows. PLoS One, 2021; 16: e0244915.
16) Ichida H, Imamura H, Yoshioka R, Mizuno T, Mise Y, Kuwatsuru R, Kawasaki S, Saiura …