Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for
3–5% of all malignant epithelial tumours. CUP is clinically characterised as an aggressive …

Cancers of unknown primary (CUPs) are histologically confirmed, metastatic malignancies
with a primary tumor site that is unidentifiable on the basis of standard evaluation and …

CUP accounts for< 5% of cancers but, because of its high mortality rate, its relative
contribution to cancer deaths is higher. 1 The incidence of CUP has been declining …

Cancers of unknown primary site (CUPs) represent a heterogeneous group of metastatic
tumours for which a standardised diagnostic work-up fails to identify the site of origin at the …

Importance For carcinoma of unknown primary site (CUP), determining the primary tumor
site may be uninformative and often does not improve outcome. Objective To discover …

Cancer of unknown primary (CUP) is an enigmatic disease entity encompassing
heterogeneous malignancies without a detectable primary tumour, despite a thorough …

In an era of advanced diagnostics, metastasis to cervical lymph nodes from an occult
primary tumor is a rare clinical entity and accounts for approximately 3% of head and neck …

Carcinoma of unknown primary (CUP) is a rare and difficult-to-treat malignancy, the
management of which might be improved by the identification of actionable driver mutations …

Cancer of unknown primary (CUP) is a rare malignancy that presents with metastatic
disease and no identifiable site of origin. Most patients have unfavorable features and …

Cancer of unknown primary (CUP) is a well recognized clinical syndrome, accounting for 3–
5% of all malignancies. It is characterized as a disease with an early dissemination of …