The relationship of ketogenic diet with neurodegenerative and psychiatric diseases: a scoping review from basic research to clinical practice
Background: The ketogenic diet (KD) has become widespread for the therapy of epileptic
pathology in childhood and adulthood. In the last few decades, the current re-emergence of …
pathology in childhood and adulthood. In the last few decades, the current re-emergence of …
Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases
J Jang, SR Kim, JE Lee, S Lee, HJ Son… - International journal of …, 2023 - mdpi.com
Ketone bodies (KBs), such as acetoacetate and β-hydroxybutyrate, serve as crucial
alternative energy sources during glucose deficiency. KBs, generated through ketogenesis …
alternative energy sources during glucose deficiency. KBs, generated through ketogenesis …
Ketogenic diet and β-Hydroxybutyrate alleviate ischemic brain injury in mice via an IRAKM-dependent pathway
C Lin, S Wang, J Xie, J Zhu, J Xu, K Liu, J Chen… - European Journal of …, 2023 - Elsevier
Ketogenic diet (KD) is a classical nonpharmacological therapy that has recently been shown
to benefit cerebral ischemia, but the mechanism remains unclear. This study investigated the …
to benefit cerebral ischemia, but the mechanism remains unclear. This study investigated the …
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice
X Tan, X Li, R Li, W Meng, Z Xie, J Li, Y Pang… - Experimental …, 2024 - Elsevier
Background Both glymphatic system dysfunction and inflammatory response aggravate
neurological dysfunction after subarachnoid hemorrhage (SAH). Studies have shown that β …
neurological dysfunction after subarachnoid hemorrhage (SAH). Studies have shown that β …
Exploring the impact of ketogenic diet on multiple sclerosis: obesity, anxiety, depression, and the glutamate system
JER Ortí, M Cuerda-Ballester… - Frontiers in …, 2023 - frontiersin.org
Background Multiple sclerosis (MS) is a neurodegenerative disorder. Individuals with MS
frequently present symptoms such as functional disability, obesity, and anxiety and …
frequently present symptoms such as functional disability, obesity, and anxiety and …
Sleep, mood disorders, and the ketogenic diet: potential therapeutic targets for bipolar disorder and schizophrenia
Bipolar disorder and schizophrenia are serious psychiatric conditions that cause a
significant reduction in quality of life and shortened life expectancy. Treatments including …
significant reduction in quality of life and shortened life expectancy. Treatments including …
The impact of ketogenic diet on the onset and progression of multiple sclerosis
JD Brockhoff, S Bereswill… - European Journal of …, 2023 - akjournals.com
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS) characterized by inflammation and neurodegeneration. Current research suggests …
(CNS) characterized by inflammation and neurodegeneration. Current research suggests …
ADCY3: the pivotal gene in classical ketogenic diet for the treatment of epilepsy
M Lin, J Gong, L Wu, X Lin, Y Zhang, W Lin… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective Epilepsy is a common neurological disorder characterized by recurrent epilepsy
episodes. As a non-pharmacological treatment, the ketogenic diet has been widely applied …
episodes. As a non-pharmacological treatment, the ketogenic diet has been widely applied …
Inflammation and oxidative stress in epileptic children: from molecular mechanisms to clinical application of ketogenic diet
A Ildarabadi, SN Mir Mohammad Ali… - Reviews in the …, 2024 - degruyter.com
Childhood epilepsy affects up to 1% of children. It has been shown that 30% of patients are
resistant to drug treatments, making further investigation of other potential treatment …
resistant to drug treatments, making further investigation of other potential treatment …
Regulation of Neuronal Plasticity Associated with Neuropsychiatric Disorders by the Orexinergic System
F Cao, Z Guo, X Ma, X Li, Q Wang - Heliyon, 2024 - cell.com
Orexins are a family of neuropeptides secreted by neurons in the lateral hypothalamus (LH).
These peptides act widespreadly across the body by interacting with specific orexin …
These peptides act widespreadly across the body by interacting with specific orexin …