Asthma affects all portions of the airways. Small airways, however, comprise a substantial
component of the conducting lung air flow. In asthma, inflammatory processes can affect the …

Abstract The Global Initiative for Asthma recommends a stepwise approach to adjust asthma
treatment to the needs of individual patients; inhaled corticosteroids (ICS) remain the core …

ABSTRACT Introduction: The use of LAMAs in asthma is now supported by pharmacological
and clinical evidence, whereas the effectiveness of therapy with ICS/LABA/LAMA fixed dose …

Introduction The increased acetylcholine signaling in asthma pathophysiology offers the
rationale for the use of LAMAs in the treatment of asthmatic patients. Tiotropium is still the …

Rationale. We previously demonstrated increased expression of programmed cell death 5
(PDCD5) in asthmatic patients and ovalbumin‐induced allergic asthma. International …

Introduction There is increasing evidence that tiotropium, a long-acting muscarinic agent
(LAMA), is useful in the presence of severe-uncontrolled asthma despite the optimization of …

Exercise induced bronchial (EIB) constriction is a common and highly specific feature of
pediatric asthma and should be diagnosed with an exercise challenge test (ECT). The …

Течение бронхиальной астмы (БА) сопровождается патологическими изменениями
бронхолегочной и сердечно-сосудистой систем (ССС). Степень выраженности …

Asthma is a chronic disorder of the airways characterized by variable and recurring airway
inflammation, bronchial hyperresponsiveness, bronchoconstriction, vasodilatation, airway …

Introdução: A crise asmática é uma exacerbação da asma que afeta a qualidade de vida do
paciente de maneira súbita, gerando prejuízos pessoais e à saúde pública, e exigindo um …