Clinicians have hypothesized a spectrum of minor neurologic manifestations, consistent with
neuroanatomical reports and collectively termed as a “syndrome of bilirubin-induced …

Most preterm infants less than 35 weeks gestational age (GA) have elevated total
serum/plasma bilirubin (TB) levels, which often present as jaundice, the yellowish …

The potential for bilirubin-induced neurotoxicity in the premature neonate (< 37 weeks
gestational age [GA]) remains a clinical concern. In addition to classic kernicterus, the …

Bilirubin encephalopathy/kernicterus is relatively rare, but continues to occur despite
universal newborn screening. What is more interesting is the spectrum of clinical and even …

Early clinical jaundice or rapidly developing hyperbilirubinemia is often a sign of hemolysis,
the differential diagnosis of which commonly includes immune-mediated disorders, red cell …

The primary goal of the evaluation and management of unconjugated hyperbilirubinemia in
premature infants is to prevent acute and chronic bilirubin-induced neurotoxicity, a spectrum …

Background and Objective: The abnormal T1-weighted imaging of MRI can be used to
characterize neonatal acute bilirubin encephalopathy (ABE) in newborns, but has limited …

Introduction: Very preterm infants are susceptible to bilirubin neurotoxicity, the signs of which
are unclear during early infancy. We investigated children born preterm and later diagnosed …

Background Differentiating acute bilirubin encephalopathy (ABE) from non-ABE in neonates
with hyperbilirubinemia (HB) from routine magnetic resonance imaging (MRI) is extremely …

Premature infants have a higher incidence of indirect hyperbilirubinemia than term infants.
Management of neonatal indirect hyperbilirubinemia in late preterm and term neonates has …