Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing
CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
Innate humoral immune defences in mammals and insects: The same, with differences?
G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …
of mammals and a wide range of insects is now employed to assess the virulence of …
From flies to men: ROS and the NADPH oxidase in phagocytes
The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …
An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes
N Browne, M Heelan, K Kavanagh - Virulence, 2013 - Taylor & Francis
The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …
to the innate immune system of mammals. As a result of these conserved features insects …
Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …
community. Larvae of Galleria mellonella are a widely used model for studying …
Immune Response of Galleria mellonella against Human Fungal Pathogens
N Trevijano-Contador, O Zaragoza - Journal of Fungi, 2018 - mdpi.com
In many aspects, the immune response against pathogens in insects is similar to the innate
immunity in mammals. This has caused a strong interest in the scientific community for the …
immunity in mammals. This has caused a strong interest in the scientific community for the …
The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest
K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …
Accumulation and trafficking of zinc oxide nanoparticles in an invertebrate model, Bombyx mori, with insights on their effects on immuno-competent cells
AH Mir, A Qamar, I Qadir, AH Naqvi, R Begum - Scientific reports, 2020 - nature.com
Abstract Zinc oxide nanoparticles (ZnO NPs) are used in many applications; however, their
interactions with cells, immune cells in particular, and potential health risk (s) are not fully …
interactions with cells, immune cells in particular, and potential health risk (s) are not fully …
[HTML][HTML] Invertebrate models of fungal infection
The morbidity, mortality and economic burden associated with fungal infections, together
with the emergence of fungal strains resistant to current antimicrobial agents, necessitate …
with the emergence of fungal strains resistant to current antimicrobial agents, necessitate …
Aspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF …
Many cystic fibrosis (CF) airway infections are considered to be polymicrobial and microbe–
microbe interactions may play an important role in disease pathology. Pseudomonas …
microbe interactions may play an important role in disease pathology. Pseudomonas …