[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers

J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Molecular dynamics and diffusion in amorphous solid dispersions containing imidacloprid

A Mansuri, P Munzner, A Heermant… - Molecular …, 2023 - ACS Publications
The main goal of this study is to develop an experimental toolbox to estimate the self-
diffusion coefficient of active ingredients (AI) in single-phase amorphous solid dispersions …

Moisture-induced limited recrystallization may not reduce the dissolution of amorphous solid dispersions: A case of nitrendipine

P Zhao, H Wang, J Jia, D Song, L Yang, X Tang… - Journal of Industrial and …, 2024 - Elsevier
As a promising strategy, amorphous solid dispersion (ASD) technology has been widely
studied and employed. However, moisture affects the physical stability of ASD, leading to …

Predicting self-diffusion coefficients in semi-crystalline and amorphous solid dispersions using free volume theory

A Mansuri, M Völkel, D Mihiranga, T Feuerbach… - European Journal of …, 2023 - Elsevier
The self-diffusion coefficient of active ingredients (AI) in polymeric solid dispersions is one of
the essential parameters for the rational formulation design in life sciences. Measuring this …

[HTML][HTML] Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product

J Figueiredo, M Mendes, A Pais, J Sousa… - Drug Delivery and …, 2024 - Springer
The fundamental idea underlying the use of amorphous solid dispersions (ASDs) is to make
the most of the solubility advantage of the amorphous form of a drug. However, the drug …

[HTML][HTML] Introducing the Molecular Pharmaceutics Special Issue on Industrial Drug Delivery─ In Silico to Bedside

L Zhou, A Bak, K Hyodo… - Molecular …, 2023 - ACS Publications
It is certainly an exciting era for scientists engaging in the formulation and drug delivery
space. In the past decades, while continuously playing a central role in drug development …