[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers
J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
Molecular dynamics and diffusion in amorphous solid dispersions containing imidacloprid
A Mansuri, P Munzner, A Heermant… - Molecular …, 2023 - ACS Publications
The main goal of this study is to develop an experimental toolbox to estimate the self-
diffusion coefficient of active ingredients (AI) in single-phase amorphous solid dispersions …
diffusion coefficient of active ingredients (AI) in single-phase amorphous solid dispersions …
Moisture-induced limited recrystallization may not reduce the dissolution of amorphous solid dispersions: A case of nitrendipine
P Zhao, H Wang, J Jia, D Song, L Yang, X Tang… - Journal of Industrial and …, 2024 - Elsevier
As a promising strategy, amorphous solid dispersion (ASD) technology has been widely
studied and employed. However, moisture affects the physical stability of ASD, leading to …
studied and employed. However, moisture affects the physical stability of ASD, leading to …
[HTML][HTML] A Monte Carlo simulation of tracer diffusion in amorphous polymers
A Mansuri, P Vora, T Feuerbach, J Winck… - Soft Matter, 2024 - pubs.rsc.org
Tracer diffusion in amorphous polymers is a sought-after quantity for a range of
technological applications. In this regard, a quantitative description of the so-called …
technological applications. In this regard, a quantitative description of the so-called …
[HTML][HTML] Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product
The fundamental idea underlying the use of amorphous solid dispersions (ASDs) is to make
the most of the solubility advantage of the amorphous form of a drug. However, the drug …
the most of the solubility advantage of the amorphous form of a drug. However, the drug …
Predicting self-diffusion coefficients in semi-crystalline and amorphous solid dispersions using free volume theory
A Mansuri, M Völkel, D Mihiranga, T Feuerbach… - European Journal of …, 2023 - Elsevier
The self-diffusion coefficient of active ingredients (AI) in polymeric solid dispersions is one of
the essential parameters for the rational formulation design in life sciences. Measuring this …
the essential parameters for the rational formulation design in life sciences. Measuring this …
[HTML][HTML] An experimental toolbox for the physical characterization of thermal insulating polymeric foams
Recent advancements in polymer science and manufacturing technologies triggered new
developments of porous materials used for mitigating heat losses, such as thermal insulating …
developments of porous materials used for mitigating heat losses, such as thermal insulating …
[HTML][HTML] Introducing the Molecular Pharmaceutics Special Issue on Industrial Drug Delivery─ In Silico to Bedside
L Zhou, A Bak, K Hyodo… - Molecular …, 2023 - ACS Publications
It is certainly an exciting era for scientists engaging in the formulation and drug delivery
space. In the past decades, while continuously playing a central role in drug development …
space. In the past decades, while continuously playing a central role in drug development …