Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T Xie… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Supramolecular assembly strategy towards organic luminescent materials

C Yin, ZA Yan, X Ma - Chemical Communications, 2023 - pubs.rsc.org
Supramolecular organic luminescent materials with different dimensionalities usually exhibit
different optical properties as well as their potential applications in various fields. Recent …

[HTML][HTML] Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery

Z Sang, L Xu, R Ding, M Wang, X Yang, X Li… - Nature …, 2023 - nature.com
The oral delivery of nano-drug delivery systems (Nano-DDS) remains a challenge. Taking
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles …

Exact solution of the Langmuir rate equation: New Insights into pseudo-first-order and pseudo-second-order kinetics models for adsorption

R Ezzati, S Ezzati, M Azizi - Vacuum, 2024 - Elsevier
The Langmuir adsorption rate equation was obtained in its exact, linear, and simple form.
Using Stochastic Numerical Simulation, it was demonstrated that this equation can …

Specific interaction based drug loading strategies

H Yu, S Zhang, H Yang, J Miao, X Ma, W Xiong… - Nanoscale …, 2023 - pubs.rsc.org
Drug carriers have been commonly used for drug control release, enhancing drug efficacy
and/or minimizing side-effects. However, it is still difficult to get a high loading efficiency …

pH-Sensitive Biomimetic Nanosystem Based on Large-Pore Mesoporous Silica Nanoparticles with High Hyaluronidase Loading for Tumor Deep Penetration

X Song, CL Li, N Qiu, QY Lv, X Wu… - ACS Applied Materials & …, 2023 - ACS Publications
Loading hyaluronidase (Hyal) in a nanocarrier is a potent strategy to degrade the tumor
extracellular matrix for tumor deep penetration and enhanced tumor therapy. Herein, a pH …

Enantioselective oral absorption of molecular chiral mesoporous silica nanoparticles

Y Wang, L Zhao, Y Dai, M Xu, R Zhou… - Advanced …, 2023 - Wiley Online Library
Inspired by the unique pharmacological effects of chiral drugs in the asymmetrical body
environments, it is assumed that the chirality of nanocarriers is also a key factor to determine …

Chirality of Copper–Amino Acid Nanoparticles Determines Chemodynamic Cancer Therapeutic Outcome

S Wang, Y Zhao, S Yao, Z Wang, Z Zhang, K Wen… - Small, 2024 - Wiley Online Library
Chirality is a prevalent characteristic in nature, where biological systems exhibit a significant
preference for specific enantiomers of biomolecules. However, there is a limited exploration …

The pro-absorptive effect of glycosylated zein-fatty acid complexes on fucoxanthin via the lipid transporter protein delivery pathway

H Kuang, X Peng, Y Liu, D Li - Food Chemistry, 2024 - Elsevier
Growing research confirms that lipid transport proteins play a key role in the trans-intestinal
epithelial transport of carotenoids. In this study, to simultaneously improve the digestive …

A new insight into the surface adsorption in the solution phase: A modification of the Langmuir isotherm

R Ezzati - Water Environment Research, 2024 - Wiley Online Library
The Langmuir isotherm, originally developed to study the adsorption of gases, has been
modified in this research to investigate the adsorption of solutes in the solution phase. The …