Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Understanding resilience: New approaches for preventing and treating PTSD

SR Horn, DS Charney, A Feder - Experimental neurology, 2016 - Elsevier
All individuals experience stressful life events, and up to 84% of the general population will
experience at least one potentially traumatic event. In some cases, acute or chronic …

Emotion and cognition interactions in PTSD: a review of neurocognitive and neuroimaging studies

JP Hayes, MB VanElzakker, LM Shin - Frontiers in integrative …, 2012 - frontiersin.org
Posttraumatic stress disorder (PTSD) is a psychiatric syndrome that develops after exposure
to terrifying and life-threatening events including warfare, motor-vehicle accidents, and …

Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory

EF Pace-Schott, A Germain, MR Milad - Biology of mood & anxiety …, 2015 - Springer
Post-traumatic stress disorder (PTSD) is accompanied by disturbed sleep and an impaired
ability to learn and remember extinction of conditioned fear. Following a traumatic event, the …

Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder

EM Glover, T Jovanovic, KB Mercer, K Kerley… - Biological …, 2012 - Elsevier
BACKGROUND: Women are twice as likely to develop posttraumatic stress disorder (PTSD)
than men. As shown in our previous work, the inability to suppress fear responses in safe …

Emotion regulation difficulties as a prospective predictor of posttraumatic stress symptoms following a mass shooting

JR Bardeen, MJ Kumpula, HK Orcutt - Journal of anxiety disorders, 2013 - Elsevier
A strong positive association between emotion regulation difficulties (ERD) and
posttraumatic stress symptoms (PTSS) has been consistently evidenced in cross-sectional …

Reward devaluation: Dot-probe meta-analytic evidence of avoidance of positive information in depressed persons.

ES Winer, T Salem - Psychological bulletin, 2016 - psycnet.apa.org
Cognitive theories of depression and anxiety have traditionally emphasized the role of
attentional biases in the processing of negative information. The dot-probe task has been …

Effect of attention training on attention bias variability and PTSD symptoms: Randomized controlled trials in Israeli and US combat veterans

AS Badura-Brack, R Naim, TJ Ryan… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Attention allocation to threat is perturbed in patients with posttraumatic stress
disorder (PTSD), with some studies indicating excess attention to threat and others …

Hsp90 and FKBP51: complex regulators of psychiatric diseases

M Criado-Marrero, T Rein… - … of the Royal …, 2018 - royalsocietypublishing.org
Mood disorders affect nearly a quarter of the world's population. Therefore, understanding
the molecular mechanisms underlying these conditions is of great importance. FK-506 …