Pulmonary function testing in COPD: looking beyond the curtain of FEV1

S Kakavas, OS Kotsiou, F Perlikos, M Mermiri… - NPJ primary care …, 2021 - nature.com
Chronic obstructive pulmonary disease (COPD) management remains challenging due to
the high heterogeneity of clinical symptoms and the complex pathophysiological basis of the …

Systematic review of telemonitoring in COPD: an update

C Pedone, D Lelli - Advances in Respiratory Medicine, 2015 - mdpi.com
Telemedicine may support individual care plans in people with chronic obstructive
pulmonary disease (COPD), potentially improving the clinical outcomes. To-date there is no …

Cardiovascular safety of tiotropium in patients with COPD

B Celli, M Decramer, I Leimer, U Vogel, S Kesten… - Chest, 2010 - Elsevier
Background The clinical trial safety database for tiotropium has been augmented with a 4-
year trial in patients with COPD, which provides an opportunity to better evaluate the …

Novel treatment strategies for smooth muscle disorders: Targeting Kv7 potassium channels

JM Haick, KL Byron - Pharmacology & therapeutics, 2016 - Elsevier
Smooth muscle cells provide crucial contractile functions in visceral, vascular, and lung
tissues. The contractile state of smooth muscle is largely determined by their electrical …

Bronchodilators: current and future

M Cazzola, MG Matera - Clinics in Chest Medicine, 2014 - chestmed.theclinics.com
The use of bronchodilators is one of the key elements in the treatment of chronic obstructive
pulmonary disease (COPD), although there is often limited reversibility of airflow obstruction …

[HTML][HTML] Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department

RB Dunne, S Shortt - The American journal of emergency medicine, 2018 - Elsevier
Introduction Projects comparing bronchodilator response by aerosol devices in the ED are
limited. Evidence suggests that the vibrating mesh nebulizer (VMN) provides 5-fold greater …

Association between peak inspiratory flow rate and hand grip muscle strength in hospitalized patients with acute exacerbation of chronic obstructive pulmonary …

A Samarghandi, OC Ioachimescu, R Qayyum - PLoS One, 2020 - journals.plos.org
Rationale Ineffective peak inspiratory flow rate (PIFR) generation in patients using inhalers
results in insufficient drug delivery to the lungs and poor clinical outcomes. Low inspiratory …

Chronic obstructive pulmonary disease diagnosis and management in older adults

NS Gooneratne, NP Patel… - Journal of the American …, 2010 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) in older adults is a complex disorder with
several unique age‐related aspects. Underlying changes in pulmonary lung function and …

Tiotropium HandiHaler® in the treatment of COPD: A safety review

S Kesten, B Celli, M Decramer, I Leimer… - International journal of …, 2009 - Taylor & Francis
Background Tiotropium is a long-acting inhaled anticholinergic developed for the treatment
of chronic obstructive pulmonary disease (COPD) and has been available since 2002. We …

[HTML][HTML] Effect of liuweibuqi capsules in pulmonary alveolar epithelial cells and COPD through JAK/STAT pathway

C Wang, H Ding, X Tang, Z Li, L Gan - Cellular Physiology and …, 2017 - karger.com
Background/Aims: To evaluate the effect of Liuweibuqi capsules on chronic obstructive
pulmonary disease (COPD) through the JAK/STAT pathway. Methods: Lung function was …