Mesothelin secretion by pancreatic cancer cells co-opts macrophages and promotes metastasis

T Luckett, M Abudula, L Ireland, M Glenn, G Bellomo… - Cancer Research, 2024 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease, yet effective
treatments to inhibit PDAC metastasis are lacking. The rich PDAC tumor microenvironment …

[HTML][HTML] The potential therapeutic benefits of Huaier in digestive system cancer: Its chemical components, pharmacological applications and future direction

H Tang, Y Yi, Y Yang, Q Dai, Z Zhao, N Jiang… - Journal of Functional …, 2024 - Elsevier
Huaier, derived from the fungus on Sophora japonica trees, is a fruiting body belonging to
Polyporaceae family. Traditionally, it has been utilized for treating hemorrhoids and rectal …

Harnessing Plant Flavonoids to Fight Pancreatic Cancer

C Niu, J Zhang, PI Okolo - Current Nutrition Reports, 2024 - Springer
This review provides strong evidence that plant flavonoids have potential against pancreatic
carcinogenesis in experimental animals through various pharmacological mechanisms …

Ultrasound-Induced Thermal Effect Enhances the Efficacy of Chemotherapy and Immunotherapy in Tumor Treatment

Y Xiang, L Tang, H Pang, H Xu, Y He… - International Journal …, 2024 - Taylor & Francis
Background The inadequate perfusion, frequently resulting from abnormal vascular
configuration, gives rise to tumor hypoxia. The presence of this condition hinders the …

Vasohibin-2-Targeting Therapies for the Treatment of Pancreatic Ductal Adenocarcinoma

Y Suzuki, Y Sato - The Tohoku Journal of Experimental Medicine, 2024 - jstage.jst.go.jp
As pancreatic ductal adenocarcinoma (PDAC) is extremely malignant and refractory,
therapeutic options for this cancer are anticipated worldwide. We isolated vasohihibin-2 …

KDM6A promotes angiogenesis, migration, and invasion of pancreatic cancer via activating LAMP3

L Xu, S Fan, D Xie, Y Yu - Critical Reviews™ in Eukaryotic Gene … - dl.begellhouse.com
ABSTRACT KDM6A is abnormally expressed in various cancer. This study aimed to
investigate the potential of KDM6A in pancreatic cancer (PC). mRNA expression was …