NAFLD: mechanisms, treatments, and biomarkers
F Nassir - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is currently the world's most common liver
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …
Mitochondria as a therapeutic target for common pathologies
MP Murphy, RC Hartley - Nature Reviews Drug Discovery, 2018 - nature.com
Although the development of mitochondrial therapies has largely focused on diseases
caused by mutations in mitochondrial DNA or in nuclear genes encoding mitochondrial …
caused by mutations in mitochondrial DNA or in nuclear genes encoding mitochondrial …
Reactive oxygen species induce fatty liver and ischemia-reperfusion injury by promoting inflammation and cell death
S Tang, X Mao, Y Chen, L Yan, L Ye, S Li - Frontiers in immunology, 2022 - frontiersin.org
Liver transplantation is the ultimate method for treating end-stage liver disease. With the
increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a …
increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a …
Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …
Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …
build-up, has been growing in the global world in concert with the raised prevalence of …
Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?
A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …
Metabolic syndrome and associated diseases: from the bench to the clinic
DL Mendrick, AM Diehl, LS Topor… - Toxicological …, 2018 - academic.oup.com
Abstract Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic, a
Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …
Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …
[HTML][HTML] Pathogenesis and prevention of hepatic steatosis
Hepatic steatosis is defined as intrahepatic fat of at least 5% of liver weight. Simple
accumulation of triacylglycerols in the liver could be hepatoprotective; however, prolonged …
accumulation of triacylglycerols in the liver could be hepatoprotective; however, prolonged …
Targeting oxidative stress for the treatment of liver fibrosis
T Luangmonkong, S Suriguga, HAM Mutsaers… - Reviews of Physiology …, 2018 - Springer
Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …