Ferroptosis in gastrointestinal cancer: from mechanisms to implications

R Zhang, R Kang, D Tang - Cancer Letters, 2023 - Elsevier
Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Ferroptosis: a double-edged sword in gastrointestinal disease

C Xu, Z Liu, J Xiao - International Journal of Molecular Sciences, 2021 - mdpi.com
Ferroptosis is a novel form of regulated cell death (RCD) that is typically accompanied by
iron accumulation and lipid peroxidation. In contrast to apoptosis, autophagy, and …

Identification of HMOX1 as a critical ferroptosis-related gene in atherosclerosis

D Wu, Q Hu, Y Wang, M Jin, Z Tao… - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Ferroptosis is a novel form of programmed iron-dependent cell death. The ferroptosis-
related genes (FRGs) have been recognized as biomarkers for cancers. Increasing …

Natural products for the management of castration-resistant prostate cancer: Special focus on nanoparticles based studies

RK Singla, CS Sai, H Chopra, S Behzad… - Frontiers in cell and …, 2021 - frontiersin.org
Prostate cancer is the most common type of cancer among men and the second most
frequent cause of cancer-related mortality around the world. The progression of advanced …

[HTML][HTML] Establishment of a novel ferroptosis-related lncRNA pair prognostic model in colon adenocarcinoma

H Li, L Liu, T Huang, M Jin, Z Zheng, H Zhang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have been reported to be prognostic factors for cancer.
Ferroptosis is an iron-dependent process of programmed cell death. Here, we established a …

Non-canonical programmed cell death in colon cancer

B Pan, B Zheng, C Xing, J Liu - Cancers, 2022 - mdpi.com
Simple Summary Non-canonical PCD is an important player in colon cancer cell suicide. It
influences colon cancer in many ways, such as through tumorigenesis, treatment, and …

Prognostic roles of ceRNA network-based signatures in gastrointestinal cancers

X Qi, X Chen, Y Zhao, J Chen, B Niu, B Shen - Frontiers in oncology, 2022 - frontiersin.org
Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten
human health around the world. Their complexity and heterogeneity make the classic …

B7H3 increases ferroptosis resistance by inhibiting cholesterol metabolism in colorectal cancer

H Jin, M Zhu, D Zhang, X Liu, Y Guo, L Xia… - Cancer …, 2023 - Wiley Online Library
Ferroptosis, a newly discovered form of regulated cell death, has been reported to be
associated with multiple cancers, including colorectal cancer (CRC). However, the …

[HTML][HTML] Extracellular matrix-based gene signature for predicting prognosis in colon cancer and immune microenvironment

R Chai, Z Su, Y Zhao, W Liang - Translational Cancer Research, 2023 - ncbi.nlm.nih.gov
Background The extracellular matrix (ECM) plays a vital role in progression, expansion, and
prognosis of malignancies. In this study, we aimed to explore a novel ECM-based prognostic …

ZNF643/ZFP69B Exerts Oncogenic Properties and Associates with Cell Adhesion and Immune Processes

U Oleksiewicz, M Machnik, J Sobocińska… - International Journal of …, 2023 - mdpi.com
The global cancer burden remains high; thus, a better understanding of the molecular
mechanisms driving carcinogenesis is needed to improve current prevention and treatment …