[HTML][HTML] Molecular mechanisms of cardiac pathology in diabetes–Experimental insights
U Varma, P Koutsifeli, VL Benson, KM Mellor… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Diabetic cardiomyopathy is a distinct pathology independent of co-morbidities such as
coronary artery disease and hypertension. Diminished glucose uptake due to impaired …
coronary artery disease and hypertension. Diminished glucose uptake due to impaired …
Glucagon‐like peptide‐1 ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via the PPAR α pathway
Lipotoxicity cardiomyopathy is the result of excessive accumulation and oxidation of toxic
lipids in the heart. It is a major threat to patients with diabetes. Glucagon‐like peptide‐1 …
lipids in the heart. It is a major threat to patients with diabetes. Glucagon‐like peptide‐1 …
Cardiac inflammation and fibrosis following chemo/radiation therapy: mechanisms and therapeutic agents
The incidence of cardiovascular disorders is one of the most concerns among people who
underwent cancer therapy. The heart side effects of cancer therapy may occur during …
underwent cancer therapy. The heart side effects of cancer therapy may occur during …
[HTML][HTML] Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice
Recent evidence indicates that toll-like receptor (TLR) 2 and 4 are involved in the
pathogenesis of dilated cardiomyopathy (DCM), but the exact mechanisms of their actions …
pathogenesis of dilated cardiomyopathy (DCM), but the exact mechanisms of their actions …
Phospholamban Ablation Rescues Sarcoplasmic Reticulum Ca2+ Handling but Exacerbates Cardiac Dysfunction in CaMKIIδC Transgenic Mice
T Zhang, T Guo, S Mishra, ND Dalton… - Circulation …, 2010 - Am Heart Assoc
Rationale: We previously showed that transgenic mice expressing Ca2+/calmodulin-
dependent protein kinase II δC (CaMKII-TG) develop dilated cardiomyopathy associated …
dependent protein kinase II δC (CaMKII-TG) develop dilated cardiomyopathy associated …
Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond
J Zhang, D Liu, M Zhang… - British journal of …, 2019 - Wiley Online Library
Excessive death of cardiac myocytes leads to many cardiac diseases, including myocardial
infarction, arrhythmia, heart failure and sudden cardiac death. For the last several decades …
infarction, arrhythmia, heart failure and sudden cardiac death. For the last several decades …
MicroRNAs regulate mitochondrial apoptotic pathway in myocardial ischemia-reperfusion-injury
P Makhdoumi, A Roohbakhsh, G Karimi - Biomedicine & Pharmacotherapy, 2016 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene
regulators. They are involved in the pathogenesis of different disorders including heart …
regulators. They are involved in the pathogenesis of different disorders including heart …
Role of cAMP in cardiomyocyte viability: beneficial or detrimental?
BACKGROUND: 3′, 5′-cyclic AMP (cAMP) regulates numerous cardiac functions. Various
hormones and neurotransmitters elevate intracellular cAMP (i [cAMP]) in cardiomyocytes …
hormones and neurotransmitters elevate intracellular cAMP (i [cAMP]) in cardiomyocytes …
Role of cardiac magnetic resonance in the evaluation of dilated cardiomyopathy: diagnostic contribution and prognostic significance
M Francone - International Scholarly Research Notices, 2014 - Wiley Online Library
Dilated cardiomyopathy (DCM) represents the final common morphofunctional pathway of
various pathological conditions in which a combination of myocyte injury and necrosis …
various pathological conditions in which a combination of myocyte injury and necrosis …
The role of miR-214 in cardiovascular diseases
Y Zhao, M Ponnusamy, L Zhang, Y Zhang, C Liu… - European journal of …, 2017 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death throughout the world. The
increase in new patients every year leads to a demand for the identification of valid and …
increase in new patients every year leads to a demand for the identification of valid and …