[HTML][HTML] Comparative roles of IL-1, IL-6, IL-10, IL-17, IL-18, 1L-22, IL-33, and IL-37 in various cardiovascular diseases with potential insights for targeted …

M Abubakar, HF Rasool, I Javed, S Raza, L Abang… - Cureus, 2023 - ncbi.nlm.nih.gov
In recent years, the study of interleukins (ILs), crucial cytokines involved in immune response
and inflammation, has garnered significant attention within the sphere of cardiovascular …

Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide

XL Louis, R Murphy, SJ Thandapilly, L Yu… - … and alternative medicine, 2012 - Springer
Background In ancient times, plants were recognized for their medicinal properties. Later,
the arrival of synthetic drugs pushed it to the backstage. However, from being merely used …

Lycopene attenuates inflammation and apoptosis in post‑myocardial infarction remodeling by inhibiting the nuclear factor‑κB signaling pathway

QIN He, WEI Zhou, C Xiong… - Molecular Medicine …, 2015 - spandidos-publications.com
Inflammatory response and cardiomyocyte apoptosis are important processes in ventricular
remodeling post‑myocardial infarction (MI) and may form the basic mechanisms in the …

Early long‐term L‐T3 replacement rescues mitochondria and prevents ischemic cardiac remodelling in rats

F Forini, V Lionetti, H Ardehali, A Pucci… - Journal of Cellular …, 2011 - Wiley Online Library
Abstract 3, 5, 3′‐Levo‐triiodothyronine (L‐T3) is essential for DNA transcription,
mitochondrial biogenesis and respiration, but its circulating levels rapidly decrease after …

Targeting necroptotic cell death pathway by high-intensity interval training (HIIT) decreases development of post-ischemic adverse remodelling after myocardial …

A Ghardashi Afousi, A Gaeini, K Rakhshan… - Journal of cell …, 2019 - Springer
Regulated necrosis (necroptosis) plays a pivotal role in the extent of cardiomyocyte loss and
the development of post-ischemic adverse remodelling and cardiac dysfunction following …

Mitochondria as key targets of cardioprotection in cardiac ischemic disease: role of thyroid hormone triiodothyronine

F Forini, G Nicolini, G Iervasi - International Journal of Molecular Sciences, 2015 - mdpi.com
Ischemic heart disease is the major cause of mortality and morbidity worldwide. Early
reperfusion after acute myocardial ischemia has reduced short-term mortality, but it is also …

Molecular mechanisms that differentiate apoptosis from programmed necrosis

GW Dorn - Toxicologic pathology, 2013 - journals.sagepub.com
Programmed cell death is physiological when disposing of senescent, dysfunctional, or
redundant cells, but pathological if these cells cannot be replaced. Mitochondria help …

miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2

D Liang, J Li, Y Wu, L Zhen, C Li, M Qi, L Wang… - International Journal of …, 2015 - Elsevier
Objectives In mammals, the heart grows by hypertrophy but not proliferation of
cardiomyocytes after birth. The paucity of cardiomyocyte proliferation limits cardiac …

[HTML][HTML] Mitochondria–cytoskeleton interaction: distribution of β-tubulins in cardiomyocytes and HL-1 cells

R Guzun, M Karu-Varikmaa… - … Et Biophysica Acta (BBA …, 2011 - Elsevier
Mitochondria–cytoskeleton interactions were analyzed in adult rat cardiomyocytes and in
cancerous non-beating HL-1 cells of cardiac phenotype. We show that in adult …

Low-intensity aerobic interval training attenuates pathological left ventricular remodeling and mitochondrial dysfunction in aortic-banded miniature swine

CA Emter, CP Baines - American Journal of Physiology …, 2010 - journals.physiology.org
Cardiac hypertrophy in response to hypertension or myocardial infarction is a pathological
indicator associated with heart failure (HF). A central component of the remodeling process …