A novel spinal neuron connection for heat sensation
Heat perception enables acute avoidance responses to prevent tissue damage and
maintain body thermal homeostasis. Unlike other modalities, how heat signals are …
maintain body thermal homeostasis. Unlike other modalities, how heat signals are …
ErbB4 regulation of a thalamic reticular nucleus circuit for sensory selection
S Ahrens, S Jaramillo, K Yu, S Ghosh, GR Hwang… - Nature …, 2015 - nature.com
Selective processing of behaviorally relevant sensory inputs against irrelevant ones is a
fundamental cognitive function whose impairment has been implicated in major psychiatric …
fundamental cognitive function whose impairment has been implicated in major psychiatric …
Hippocampal interneurons in bipolar disorder
C Konradi, EI Zimmerman, CK Yang… - Archives of general …, 2011 - jamanetwork.com
Objective: To assess hippocampal volume, neuron number, and interneurons in the same
specimens of subjects with bipolar disorder and healthy control subjects. Design: Whole …
specimens of subjects with bipolar disorder and healthy control subjects. Design: Whole …
GeneAnalytics pathway analysis and genetic overlap among autism spectrum disorder, bipolar disorder and schizophrenia
NS Khanzada, MG Butler, AM Manzardo - International Journal of …, 2017 - mdpi.com
Bipolar disorder (BPD) and schizophrenia (SCH) show similar neuropsychiatric behavioral
disturbances, including impaired social interaction and communication, seen in autism …
disturbances, including impaired social interaction and communication, seen in autism …
Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia
Objectives Aberrant DNA methylation and gene expression have been reported in
postmortem brain tissues of psychotic patients, but until now there has been no systematic …
postmortem brain tissues of psychotic patients, but until now there has been no systematic …
TDP‐43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons
BM Schwenk, H Hartmann, A Serdaroglu… - The EMBO …, 2016 - embopress.org
Nuclear clearance of TDP‐43 into cytoplasmic aggregates is a key driver of
neurodegeneration in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar …
neurodegeneration in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar …
Modeling psychiatric disorders at the cellular and network levels
Although psychiatric disorders such as autism spectrum disorders, schizophrenia and
bipolar disorder affect a number of brain regions and produce a complex array of clinical …
bipolar disorder affect a number of brain regions and produce a complex array of clinical …
Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments
T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …
relationship between small-scale dendrite morphological abnormalities (shape, density of …
Long non-coding RNAs in neuronal aging
D Pereira Fernandes, M Bitar, FMJ Jacobs, G Barry - Non-coding RNA, 2018 - mdpi.com
The expansion of long non-coding RNAs (lncRNAs) in organismal genomes has been
associated with the emergence of sophisticated regulatory networks that may have …
associated with the emergence of sophisticated regulatory networks that may have …
The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin
W Choi, R Wolber, W Gerwat, T Mann… - Journal of cell …, 2010 - journals.biologists.com
Interactions between melanocytes and neighboring cells in the skin are important in
regulating skin color in humans. We recently demonstrated that the less pigmented and …
regulating skin color in humans. We recently demonstrated that the less pigmented and …