The mechanical index (MI) has been used by the US Food and Drug Administration (FDA)
since 1992 for regulatory decisions regarding the acoustic output of diagnostic ultrasound …

Various numerical algorithms have been developed to solve the Khokhlov–Kuznetsov–
Zabolotskaya (KZK) parabolic nonlinear wave equation. In this work, a generalized time …

High intensity focused ultrasound (FUS) is a noninvasive technique for treatment of tissues
that can lie deep within the body. There is a need for methods to rapidly and quantitatively …

The possibility to apply ultrasonic waves, ie, high-frequency acoustic waves, for therapeutic
purposes was recognized over 60 years ago. Chapter 1 of this dissertation establishes the …

Background Varicose veins are a common disease that may significantly affect quality of life.
Different approaches are currently used in clinical practice to treat this pathology. Materials …

The existing safety standards for diagnostic ultrasound devices were developed for low
frequency systems (1 to 10 MHz) under the assumption that nonlinear effects are negligible …

Several approaches for simulating ultrasound are available. The main tools are Finite or
Boundary element methods and the spatial impulse response methods. Finite and Boundary …

Focused ultrasound (FUS) is a non-invasive therapeutic technology that can use ultrasonic
energy to precisely target tissue deep inside the body without incisions or radiation …

Liver transplantation is the mainstay of the treatment for end stage liver diseases including
metabolic and congenital liver diseases. The number of suitable donor organs is, however …

High intensity focused ultrasound (HIFU) devices operate at intensity levels of up to 30,000
W/cm 2 and are used to perform noninvasive thermal therapy. At these output levels …