Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Background The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after …

This review of the literature on traumatic brain injury (TBI) in older adults focuses on incident
TBI sustained in older adulthood (“geriatric TBI”) rather than on the separate, but related …

The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Background The burden of traumatic brain injury (TBI) poses a large public health and
societal problem, but the characteristics of patients and their care pathways in Europe are …

In nearly all clinical and research contexts, the initial severity of a traumatic brain injury (TBI)
is measured using the Glasgow Coma Scale (GCS) total score. The GCS total score …

Another recent debate was on the interpretation of the lack of external validation studies of
published novel prediction models [3][4][5]. One issue is the role that validation should have …

Importance After severe traumatic brain injury, induction of prophylactic hypothermia has
been suggested to be neuroprotective and improve long-term neurologic outcomes …