Neuroanatomical differences in obesity: meta-analytic findings and their validation in an independent dataset
Background Obesity has been linked with subtle differences in brain structure. These
differences tend to be especially relevant in prefrontal cortex regions, areas which play an …
differences tend to be especially relevant in prefrontal cortex regions, areas which play an …
Neurobehavioral correlates of obesity are largely heritable
Recent molecular genetic studies have shown that the majority of genes associated with
obesity are expressed in the central nervous system. Obesity has also been associated with …
obesity are expressed in the central nervous system. Obesity has also been associated with …
Obesity, dyslipidemia and brain age in first-episode psychosis
Introduction Obesity and dyslipidemia may negatively affect brain health and are frequent
medical comorbidities of schizophrenia and related disorders. Despite the high burden of …
medical comorbidities of schizophrenia and related disorders. Despite the high burden of …
Population-based research in obesity–an overview of neuroimaging studies using big data approach
In this review, we present research on neuroanatomical correlates of obesity using big data.
This approach utilizes large sample sizes from population-based cohorts and is especially …
This approach utilizes large sample sizes from population-based cohorts and is especially …
[HTML][HTML] Obesity is associated with reduced orbitofrontal cortex volume: a coordinate-based meta-analysis
Neural models of obesity vary in their focus upon prefrontal and striatal differences. Animal
and human studies suggest that differential functioning of the orbitofrontal cortex is …
and human studies suggest that differential functioning of the orbitofrontal cortex is …
[HTML][HTML] Neuroanatomical changes in white and grey matter after sleeve gastrectomy
Background MRI studies show that obese adults have reduced grey matter (GM) and white
matter (WM) tissue density as well as altered WM integrity. Bariatric surgery can lead to …
matter (WM) tissue density as well as altered WM integrity. Bariatric surgery can lead to …
Prefronto-cerebellar neuromodulation affects appetite in obesity
EM Marron, R Viejo-Sobera, G Cuatrecasas… - International journal of …, 2019 - nature.com
Human neuroimaging studies have consistently reported changes in cerebellar function and
integrity in association with obesity. To date, however, the nature of this link has not been …
integrity in association with obesity. To date, however, the nature of this link has not been …
Impulsivity and body fat accumulation are linked to cortical and subcortical brain volumes among adolescents and adults
Obesity is associated not only with metabolic and physical health conditions, but with
individual variations in cognition and brain health. This study examined the association …
individual variations in cognition and brain health. This study examined the association …
Expression of dopamine signaling genes in the post-mortem brain of individuals with mental illnesses is moderated by body mass index and mediated by insulin …
RB Mansur, GR Fries, M Subramaniapillai… - Journal of psychiatric …, 2018 - Elsevier
Preclinical studies implicate insulin signaling as a modulator of dopamine transmission, but
human data is currently limited. We hypothesize that changes in the expression of insulin …
human data is currently limited. We hypothesize that changes in the expression of insulin …
The effect of body mass index on glucagon-like peptide receptor gene expression in the post mortem brain from individuals with mood and psychotic disorders
RB Mansur, GR Fries, AP Trevizol… - European …, 2019 - Elsevier
There is an increasing interest in the putative role of glucagon-like peptide 1 receptor (GLP-
1R) agonists as novel therapeutic agents for mental disorders. Herein, we investigated the …
1R) agonists as novel therapeutic agents for mental disorders. Herein, we investigated the …