[HTML][HTML] Neural structural abnormalities behind altered brain activation in obesity: Evidence from meta-analyses of brain activation and morphometric data

L Zapparoli, F Devoto, G Giannini, S Zonca, F Gallo… - NeuroImage: Clinical, 2022 - Elsevier
Obesity represents a risk factor for disability with a major bearing on life expectancy.
Neuroimaging techniques are contributing to clarify its neurobiological underpinnings. Here …

Brain structural differences in monozygotic twins discordant for body mass index

CM Weise, T Bachmann, B Pleger - Neuroimage, 2019 - Elsevier
Background Substantial efforts have been made to investigate the neurobiological
underpinnings of human obesity with a number of studies indicating a profound influence of …

Viscoelasticity of striatal brain areas reflects variations in body mass index of lean to overweight male adults

S Hetzer, S Hirsch, J Braun, I Sack… - Brain Imaging and …, 2020 - Springer
Although a variety of MRI studies investigated the link between body mass index (BMI) and
parameters of neural gray matter (GM), the technique applied in most of these studies, voxel …

Differential impact of body mass index and leptin on baseline and longitudinal positron emission tomography measurements of the cerebral metabolic rate for glucose …

CM Weise, K Chen, Y Chen, V Devadas… - Frontiers in Aging …, 2022 - frontiersin.org
Introduction Several studies have suggested that greater adiposity in older adults is
associated with a lower risk of Alzheimer's disease (AD) related cognitive decline, some …

Differences in brain structure and function in children with the FTO obesity‐risk allele

C Lugo‐Candelas, Y Pang, S Lee, J Cha… - Obesity Science & …, 2020 - Wiley Online Library
Objective Noncoding alleles of the fat mass and obesity‐associated (FTO) gene have been
associated with obesity risk, yet the underlying mechanisms remain unknown. Risk allele …

Vulnerability of the Hippocampus to Insults: Links to Blood–Brain Barrier Dysfunction

TL Davidson, RJ Stevenson - International Journal of Molecular Sciences, 2024 - mdpi.com
The hippocampus is a critical brain substrate for learning and memory; events that harm the
hippocampus can seriously impair mental and behavioral functioning. Hippocampal …

Preliminary evidence for genetic overlap between body mass index and striatal reward response

TM Lancaster, I Ihssen, LM Brindley… - Translational Psychiatry, 2018 - nature.com
The reward-processing network is implicated in the aetiology of obesity. Several lines of
evidence suggest obesity-linked genetic risk loci (such as DRD2 and FTO) may influence …

Neuroanatomical profile of BMI implicates impulsive delay discounting and general cognitive ability

H Xu, MM Owens, J MacKillop - Obesity, 2023 - Wiley Online Library
Objective Obesity is a disorder of excessive adiposity, typically assessed via the
anthropometric density measure of BMI. Numerous studies have implicated BMI with …

Shared genetic influences on adolescent body mass index and brain structure: a voxel-based morphometry study in twins

JT Kennedy, SV Astafiev, S Golosheykin, O Korucuoglu… - Neuroimage, 2019 - Elsevier
Background Previous research has demonstrated significant relationships between obesity
and brain structure. Both phenotypes are heritable, but it is not known whether they are …

Mouse twins separated when young: A history of exploration doubles the heritability of boldness and differentially affects the heritability of measures of learning

LD Matzel, S Bendrath, M Herzfeld, DW Crawford… - Intelligence, 2019 - Elsevier
Most quantifiable traits exhibit some degree of heritability. The heritability of physical traits is
often high, but the heritability of some personality traits and intelligence can also be highly …