The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2) infection, is leading to unknown and unusual health conditions …

Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …

Coronary artery disease (CAD) and its complications are the leading cause of death
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

There is a pandemic of physical inactivity that appears to parallel the widespread
prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise …

Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …

High blood pressure (BP) is one of the main modifiable risk factors for cardiovascular
disease (CVD) and preventing it greatly reduces the vascular consequences of aging and …