Multiple endocrine neoplasia type 1: latest insights

ML Brandi, SK Agarwal, ND Perrier, KE Lines… - Endocrine …, 2021 - academic.oup.com
Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Clinical aspects of multiple endocrine neoplasia type 1

A Al-Salameh, G Cadiot, A Calender… - Nature Reviews …, 2021 - nature.com
Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by the co-
occurrence of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumours …

[HTML][HTML] Multiple endocrine neoplasia type 1 (MEN1): an update and the significance of early genetic and clinical diagnosis

CDC Kamilaris, CA Stratakis - Frontiers in endocrinology, 2019 - frontiersin.org
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

Multiple endocrine neoplasia type 1 and the pancreas: diagnosis and treatment of functioning and non-functioning pancreatic and duodenal neuroendocrine …

B Niederle, A Selberherr, DK Bartsch, ML Brandi… - …, 2021 - karger.com
The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

[HTML][HTML] Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence

I Coutinho, TK Day, WD Tilley… - Endocrine-related …, 2016 - erc.bioscientifica.com
The androgen receptor (AR) signaling axis drives all stages of prostate cancer, including the
lethal, drug-resistant form of the disease termed castration-resistant prostate cancer (CRPC) …

Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies

RM Ruggeri, E Benevento, F De Cicco… - Journal of …, 2023 - Springer
Purpose Neuroendocrine neoplasms can occur as part of inherited disorders, usually in the
form of well-differentiated, slow-growing tumors (NET). The main predisposing syndromes …

[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

Long-term natural course of small nonfunctional pancreatic neuroendocrine tumors in MEN1—results from the Dutch MEN1 Study Group

CRC Pieterman, JM De Laat, JWR Twisk… - The Journal of …, 2017 - academic.oup.com
Background Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with
multiple endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause …

Multiple endocrine neoplasia type 1

F Giusti, F Marini, F Tonelli, ML Brandi - Principles of bone biology, 2020 - Elsevier
Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome caused by
inactivating heterozygote mutations of the MEN1 gene affecting parathyroid glands …

Current and emerging therapies for PNETs in patients with or without MEN1

M Frost, KE Lines, RV Thakker - Nature Reviews Endocrinology, 2018 - nature.com
Pancreatic neuroendocrine tumours (PNETs) might occur as a non-familial isolated
endocrinopathy or as part of a complex hereditary syndrome, such as multiple endocrine …