Background Historically, malaria has been the predominant cause of acute febrile illness
(AFI) in sub-Saharan Africa. However, during the last two decades, malaria incidence has …

Background Sepsis is a global threat but insufficiently studied in Southeast Asia. The
objective was to evaluate management, outcomes, adherence to sepsis bundles, and …

Advancing Access to Diagnostic Tools Essential for Universal Health Coverage and
Antimicrobial Resistance Prevention: An Overvie Page 1 Advancing Access to Diagnostic …

Introduction Fever commonly leads to healthcare seeking and hospital admission in sub-
Saharan Africa and Asia. There is only limited guidance for clinicians managing non …

Background Epidemic arbovirus transmission occurs among humans by mosquito bites and
the sylvatic transmission cycles involving non-human primates (NHPs) still exists. However …

Background The awareness of non-malarial febrile illnesses (NMFIs) has been on the rise
over the last decades. Therefore, we undertook a systematic literature review and meta …

Flaviviruses such as Zika, dengue, and yellow fever cause epidemics throughout the tropics
and account for substantial global morbidity and mortality. Although malaria and other vector …

Background Acute undifferentiated febrile illness is a common challenge for clinicians,
especially in tropical and subtropical countries. Incorrect or delayed diagnosis of febrile …

Acute undifferentiated febrile illnesses (AUFI) are characterised by fever of less than two
weeks' duration without organ-specific symptoms at the onset. 1 These may begin with …

Typhoid fever is estimated to cause between 11.9–26.9 million infections globally each year
with 129,000–216,510 deaths. Access to improved water sources have reduced disease …