Metagenomic sequencing is a promising new method for pathogen detection. We aimed to
detect pathogens from archived plasma using metagenomic sequencing in a previously well …

Abstract Background In sub-Saharan Africa (SSA), the highly albumin-bound β-lactam
ceftriaxone is frequently used for the empirical treatment of severe bacterial infections …

In low-income and middle-income countries, most patients with febrile illnesses present to
peripheral levels of the health system where diagnostic capacity is very limited. In these …

Introduction In low-resource settings, empiric case management of febrile illness is routine
as a result of limited access to laboratory diagnostics. The use of comprehensive fever …

A systematic review and meta-analysis of the aetiological agents of non-malarial febrile
illnesses in Africa Page 1 RESEARCH ARTICLE A systematic review and meta-analysis of the …

Global health security depends on effective surveillance for infectious diseases. In Uganda,
resources are inadequate to support collection and reporting of data necessary for an …

Invasive Salmonella infection is a common cause of acute febrile illness (AFI) among
children in sub-Saharan Africa; however, diagnosing Salmonella bacteremia is challenging …

Ticks are a group of obligate blood-sucking ectoparasites that play a critical role in
transmitting several important zoonotic pathogens that can infect animals and humans …

Background Fever is the most frequent symptom in patients seeking care in South and
Southeast Asia. The introduction of rapid diagnostic tests (RDTs) for malaria continues to …

Background Primary health care settings and hospitals of low-and middle-income countries
have few accessible diagnostic tools and limited laboratory and human resources capacity …