Risks and benefits of phase I liver dysfunction studies: should patients with severe liver dysfunction be included in these trials?
C Fountzilas, S Stuart, B Hernandez… - Investigational new …, 2017 - Springer
Introduction The goal of organ dysfunction Phase I trials is to characterize the safety and
pharmacokinetics of novel agents in cancer patients with liver or kidney dysfunction, but the …
pharmacokinetics of novel agents in cancer patients with liver or kidney dysfunction, but the …