Dynorphin 1-17 biotransformation peptides: properties, challenges and solutions for future therapeutics development

R Ballouze, SM Salhimi, N Mohtar… - Future Medicinal …, 2023 - Taylor & Francis
It is well established that endogenously produced dynorphin 1-17 (DYN 1-17) is susceptible
to enzymatic degradation, producing a variety of unique fragments in different tissue …

Dynamic measurement of extracellular opioid activity: status quo, challenges, and significance in rewarded behaviors

NP Murphy - ACS Chemical Neuroscience, 2015 - ACS Publications
Opioid peptides are the endogenous ligands of opioid receptors, which are also the
molecular target of naturally occurring and synthetic opiates, such as morphine and heroin …

[HTML][HTML] Endogenous opioid levels do not correlate with itch intensity and therapeutic interventions in hepatic pruritus

MM Düll, K Wolf, M Vetter, P Dietrich… - Frontiers in …, 2021 - frontiersin.org
Background: Chronic pruritus affects up to 70% of patients with immune-mediated
hepatobiliary disorders. Antagonists of the μ-opioid receptor (MOR) and agonists of the κ …

Neprilysin inhibition, endorphin dynamics, and early symptomatic improvement in heart failure: a pilot study

E Revuelta‐López, J Núñez, P Gastelurrutia… - ESC heart …, 2020 - Wiley Online Library
Aim Sacubitril/valsartan is a first‐in‐class angiotensin receptor‐neprilysin inhibitor
developed for the treatment of heart failure with reduced ejection fraction. Its benefits are …

[HTML][HTML] Comparative study of role of physiotherapy alone versus physiotherapy combined with yoga in rehabilitation after a sports injury. What can a primary …

SK Rai, TP Gupta, GK Gupta, AB Kale… - Journal of Family …, 2022 - journals.lww.com
Background: Posttraumatic rehabilitation of sports injuries involves physiotherapy.
Additionally, nonsurgical treatment of sports injuries involves regular physiotherapy as a …

Risk Factors for Helminth Infection in Farmers: Literature Review

EH Kurniyawan - Journal of Smart Nursing and Health …, 2024 - jurnal.poltekkesbanten.ac.id
Worm infection is a serious health problem in many countries, especially in areas with poor
sanitation. The factors that contribute to worm infection can vary, including environmental …

[HTML][HTML] Evaluation of the Influence of Biological Factors during the Course of Treatment in Patients with Ovarian Cancer

D Schneider-Matyka, E Skwirczyńska, M Gaur… - International Journal of …, 2022 - mdpi.com
The aim of this study was to evaluate the influence of β-endorphins and serotonin on the
course of treatment, disease-free time, and overall survival of patients with ovarian cancer …

Pharmacology of Endogenous Opioids, Opiates and Their Receptors

MN Al–Qattan, N Das, RKP Tripathi - Frontiers in Pharmacology of …, 2020 - Springer
The search for analgesia is the main drive for the discovery of opioid receptors and their
endogenous ligand peptides. Although opioid peptides are very similar in their N-terminal …

Συγκριτική μελέτη της λαπαροσκοπικής προσπέλασης έναντι της μέσης λαπαροτομής ως προς το ρόλο του μεγέθους του χειρουργικού τραύματος στη μετεγχειρητική …

Θ Μαργετουσάκης - repo.lib.duth.gr
Purpose: The purpose of this thesis was to compare the laparoscopic approach versus the
median laparotomy in terms of the degree of activation of the postoperative systemic …

[PDF][PDF] Terapi Akupresur Dan Murottal Al-Quran Terhadap Intensitas Nyeri Dan Endorphin Urin

EH Kurniyawan, J Haryanto… - Ef Penyul Gizi … - download.garuda.kemdikbud.go.id
Sebagian besar pasien pasca bedah ORIF mengalami rasa sakit pada saat perawatan luka.
Terapi obat anti nyeri dan Pengobatan Alternatif Komplementer dapat digunakan untuk …