Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities
KH Nicolaides - American journal of obstetrics and gynecology, 2004 - Elsevier
There is extensive evidence that effective screening for major chromosomal abnormalities
can be provided in the first trimester of pregnancy. Prospective studies in a total of 200,868 …
can be provided in the first trimester of pregnancy. Prospective studies in a total of 200,868 …
Increased nuchal translucency with normal karyotype
AP Souka, CS Von Kaisenberg, JA Hyett… - American journal of …, 2005 - Elsevier
Increased fetal nuchal translucency (NT) thickness between 11 and 14 weeks' gestation is a
common phenotypic expression of chromosomal abnormalities, including trisomy 21 …
common phenotypic expression of chromosomal abnormalities, including trisomy 21 …
Maternal serum screening for Down's syndrome in early pregnancy.
NJ Wald, HS Cuckle, JW Densem, K Nanchahal… - British medical …, 1988 - bmj.com
The possibility of improving the effectiveness of antenatal screening for Down's syndrome by
measuring human chorionic gonadotrophin concentrations in maternal serum during the …
measuring human chorionic gonadotrophin concentrations in maternal serum during the …
Antenatal screening for Down's syndrome
NJ Wald, A Kennard, A Hackshaw… - Journal of Medical …, 1997 - journals.sagepub.com
Background In 1968 the first antenatal diagnosis of Down's syndrome was made and
screening on the basis of selecting women of advanced maternal age for amniocentesis was …
screening on the basis of selecting women of advanced maternal age for amniocentesis was …
Isolated sonographic markers for detection of fetal Down syndrome in the second trimester of pregnancy.
DA Nyberg, VL Souter, A El-Bastawissi… - … of Ultrasound in …, 2001 - Wiley Online Library
To determine whether sonographic" markers" are associated with fetal Down syndrome
during the second trimester and to estimate the degree of risk of individual markers using …
during the second trimester and to estimate the degree of risk of individual markers using …
Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis
R Smith-Bindman, W Hosmer, VA Feldstein, JJ Deeks… - Jama, 2001 - jamanetwork.com
ContextSecond-trimester prenatal ultrasound is widely used in an attempt to detect Down
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the …
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the …
Hydrops revisited: Literature review of 1, 414 cases published in the 1980s
GA Machin - American journal of medical genetics, 1989 - Wiley Online Library
Hydrops revisited: Literature review of 1, 414 cases published in the 1980s Page 1 American
Journal of Medical Genetics 34366 -390 (1989) Hydrops Revisited: Literature Review of 1,414 …
Journal of Medical Genetics 34366 -390 (1989) Hydrops Revisited: Literature Review of 1,414 …
The genetic sonogram: a method of risk assessment for Down syndrome in the second trimester
B Bromley, E Lieberman, TD Shipp… - Journal of Ultrasound …, 2002 - Wiley Online Library
Objective. To determine the risk of Down syndrome in fetuses with sonographic markers
using the Bayes theorem and likelihood ratios. Methods. We prospectively evaluated the …
using the Bayes theorem and likelihood ratios. Methods. We prospectively evaluated the …
Prenatal diagnosis with fetal cells isolated from maternal blood by multiparameter flow cytometry
JO Price, S Elias, SS Wachtel, K Klinger… - American journal of …, 1991 - Elsevier
A long-sought goal of medical genetics has been development of prenatal diagnostic
procedures that do not endanger the conceptus. Reliable and universal screening for …
procedures that do not endanger the conceptus. Reliable and universal screening for …
Fetal pyelectasis: a possible association with Down syndrome
BR Benacerraf, J Mandell, JA Estroff… - Obstetrics & …, 1990 - journals.lww.com
Two hundred ten consecutive fetuses were identified as having renal pyelectasis among
7400 patients scanned during 1 year. Seven of these 210 fetuses had Down syndrome. We …
7400 patients scanned during 1 year. Seven of these 210 fetuses had Down syndrome. We …