Enalapril: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

PA Todd, RC Heel - Drugs, 1986 - Springer
Synopsis: Enalapril maleate 1 is an orally active angiotensin-converting enzyme inhibitor. It
lowers peripheral vascular resistance without causing an increase in heart rate. Enalapril 10 …

Activity assays and immunoassays for plasma renin and prorenin: information provided and precautions necessary for accurate measurement

DJ Campbell, J Nussberger, M Stowasser… - Clinical …, 2009 - academic.oup.com
Background: Measurement of plasma renin is important for the clinical assessment of
hypertensive patients. The most common methods for measuring plasma renin are the …

An overview of the clinical pharmacology of enalapril.

RO Davies, HJ Gomez, JD Irvin… - British journal of clinical …, 1984 - Wiley Online Library
Enalapril maleate is a prodrug which when administered orally is hydrolysed to release the
active converting enzyme inhibitor enalaprilat. Enalapril maleate is 60% absorbed and 40 …

Lisinopril: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

SG Lancaster, PA Todd - Drugs, 1988 - Springer
Synopsis Lisinopril is an orally active angiotensin-converting enzyme (ACE) inhibitor which
at dosages of 20 to 80mg once daily is effective in lowering blood pressure in all grades of …

Enalapril: a review of human pharmacology

HJ Gomez, VJ Cirillo, JD Irvin - Drugs, 1985 - Springer
Enalapril, an orally-active, long-acting, nonsulphydryl angiotensin-converting enzyme (ACE)
inhibitor, is extensively hydrolysed in vivo to enalaprilat, its bioactive form. Bioactivation …

Clinical pharmacokinetics of the newer ACE inhibitors: a review

JG Kelly, K O'Malley - Clinical pharmacokinetics, 1990 - Springer
The orally active angiotensin-converting inhibitors (ACE inhibitors) such as captopril and
enalapril represent a significant therapeutic advance in the treatment of hypertension and …

Clinical pharmacokinetics of the angiotensin converting enzyme inhibitors: a review

SH Kubo, RJ Cody - Clinical pharmacokinetics, 1985 - Springer
The angiotensin converting enzyme inhibitors are an important therapeutic advance in the
treatment of patients with hypertension and congestive heart failure. In addition, they are …

Choosing the right ACE inhibitor: a guide to selection

G Leonetti, C Cuspidi - Drugs, 1995 - Springer
To find out if there are one or more criteria to guide selection among the ACE inhibitors for
the treatment of arterial hypertension, we have reviewed the principal pharmacokinetic and …

Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease

ML Watson, AM Macnicol, PL Allan, AF Wright - Kidney international, 1992 - Elsevier
Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease. The
pathogenesis of hypertension in autosomal-dominant polycystic kidney disease (ADPKD) is …

Captopril: pharmacokinetics, antihypertensive and biological effects in hypertensive patients.

C Richer, B Giroux, PF Plouin, B Maarek… - British journal of …, 1984 - Wiley Online Library
The kinetics of captopril plasma levels and of the drug‐induced plasma converting enzyme
activity (PCEA), plasma renin activity (PRA) and diastolic blood pressure (DBP) …