Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

Intestinal macrophages are the main participants of intestinal immune homeostasis and
intestinal inflammation. Under different environmental stimuli, intestinal macrophages can …

In this study, water-soluble polysaccharide from Arctium lappa was extracted, isolated and
purified to be a fraction (ALP-1). Characterization of structure revealed that ALP-1 was a kind …

Nuclear factor-kappa B (NF-κB) is a kind of multi-functional nuclear transcription factor
involved in regulating gene transcription to influence pathological evolution of inflammatory …

Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Abstract In China, Baitouweng Tang (BTWT) is a commonly prescribed remedy for the
treatment of ulcerative colitis (UC). Herein, the present study aims to assess the anti-colitis …

Abstract Ethnopharmacological relevance Banxia Xiexin Decoction (BXD) was first recorded
in a Chinese medical classic, Treatise on Febrile Diseases and Miscellaneous Diseases …

Lobetyolin (LBT) is a polyacetylene glycoside found in diverse medicinal plants but mainly
isolated from the roots of Codonopsis pilosula, known as Radix Codonopsis or Dangshen …

The gut microbiota, including probiotics and pathogenic microorganisms, is involved in
ulcerative colitis (UC) by regulating pathogenic microorganisms and the production of …

Berberine has demonstrated efficacy in alleviating experimental colitis in vivo and in vitro.
However, the anti-colitis mechanisms of berberine that enable it to promote intestinal barrier …