Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Next to acute sickness behavior, septic encephalopathy is the most frequent involvement of
the brain during infection. It is characterized by a cross-talk of pro-inflammatory cells across …

Background Owing to metabolic disequilibrium and immune suppression, intracerebral
hemorrhage (ICH) patients are prone to infections; according to a recent global analysis of …

Alzheimer's disease (AD) is characterized by the accumulation of specific proteins in the
brain. A recent study revealed that manipulating gut microbiota (GM) significantly reduced …

Decades of research have demonstrated an incontrovertible role of amyloid-β (Aβ) in the
etiology of Alzheimer's disease (AD). However, the overemphasis on the pathological …

Introduction Sepsis-associated encephalopathy (SAE) is a diffuse cerebral dysfunction
resulting from a systemic inflammatory response to infection; however, its pathophysiology …

Accumulating evidence has suggested that a great proportion of sepsis survivors suffer from
long-term cognitive impairments after hospital discharge, leading to decreased life quality …

Sepsis is a life-threatening state that arises due to a hyperactive inflammatory response
stimulated by infection and rarely other insults (eg, non-infections tissue injury). Although …

Abstract Sepsis-associated encephalopathy (SAE), a common neurological complication of
sepsis, is a heterogenous complex clinical syndrome caused by the dysfunctional response …

Blast exposure, commonly experienced by military personnel, can cause devastating life-
threatening polysystem trauma. Despite considerable research efforts, the impact of the …