Vertebral end-plate (Modic) changes on lumbar spine MRI: correlation with pain reproduction at lumbar discography

I Braithwaite, J White, A Saifuddin, P Renton… - European Spine …, 1998 - Springer
The vertebral end-plate has been identified as a possible source of discogenic low back
pain. MRI demonstrates end-plate (Modic) changes in 20–50% of patients with low back …

Spine infections

JL Go, S Rothman, A Prosper, R Silbergleit… - Neuroimaging Clinics of …, 2012 - Elsevier
Infections of the spine represent a rare but potentially debilitating and neurologically
devastating condition for patients. Early diagnosis, imaging, and intervention may prevent …

Incidental findings on MRI of the spine

S Kamath, N Jain, N Goyal, R Mansour, K Mukherjee - Clinical radiology, 2009 - Elsevier
MRI is widely used as the imaging of choice for spinal disorders and may reveal either a
clinically insignificant incidental abnormality or a significant lesion, unrelated to the spine …

Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro

EJ Chiu, DC Newitt, MR Segal, SS Hu, JC Lotz… - Spine, 2001 - journals.lww.com
Study Design. Twelve lumbar intervertebral disc specimens were imaged with magnetic
resonance imaging to estimate relaxation constants, T1 and T2, and tissue water diffusion …

Lactic acid and proteoglycans as metabolic markers for discogenic back pain

KR Keshari, JC Lotz, TM Link, S Hu, S Majumdar… - Spine, 2008 - journals.lww.com
Study Design. Disc tissue was removed at surgery from 9 patients with discogenic pain and
9 deformity patients with scoliosis undergoing anterior and posterior spinal fusion. These …

Systems, compositions, and methods for local imaging and treatment of pain

DS Bradford, JC Lotz - US Patent 9,161,735, 2015 - Google Patents
Pain factors are labeled with targeted agents or markers delivered into the body. The
labeled pain factors are imaged with appropriate imaging tools in a manner allowing …

Systems and methods for automated voxelation of regions of interest for magnetic resonance spectroscopy

JP Claude, JC Peacock III, PH Kane - US Patent 9,280,718, 2016 - Google Patents
A system and method for automating an appropriate voxel prescription in a uniquely
definable region of interest (ROI) in a tissue of a patient is provided, such as for purpose of …

Characterization of intervertebral disc degeneration by high‐resolution magic angle spinning (HR‐MAS) spectroscopy

KR Keshari, AS Zektzer, MG Swanson… - … in Medicine: An …, 2005 - Wiley Online Library
The goal of this study was to determine the ability of high‐resolution magic angle spinning
(HR‐MAS) NMR spectroscopy to distinguish different stages of intervertebral disc …

Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method

JC Peacock III, JP Claude, PH Kane… - US Patent …, 2015 - Google Patents
Abstract Systems and methods are provided for processing a set of multiple serially acquired
magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi …

MRI of the lumbar intervertebral disc

S Morgan, A Saifuddin - Clinical radiology, 1999 - Elsevier
The lumbar spine is one of the commonest regions of the body imaged with MRI. Various
pathological processes can involve the lumbar intervertebral disc, including degeneration …